Folic acid (pteroylmonoglutamic acid) has historically been used as the reference folate in human intervention studies assessing the relative bioavailability of dietary folate. Recent studies using labelled folates indicated different plasma response kinetics to folic acid than to natural (food) folates, thus obviously precluding its use in single-dose experiments. Since differences in tissue d...

We report the isolation, characterization and quantification of five octasaccharides, four hexasaccharides and two tetrasaccharides, derived from the chondroitin sulphate (CS) linkage region of 6-8-year-old bovine articular cartilage aggrecan, following digestion with chondroitin ABC endolyase. Using a novel high-pH anion-exchange chromatography (HPAEC) method, in conjunction with one- and two-...

An oral glucose challenge causes transient impairment of endothelial function, probably because of increased oxidative stress. During oxidative stress, endothelial nitric oxide (NO) synthase (eNOS) becomes uncoupled because of decreased bioavailability of tetrahydrobiopterin (BH4), an essential cofactor of eNOS. Therefore, we examined whether an acute supplement of BH4 could restore endothelial...

The emergence of high-resolution satellites with new spectral channels and the ability to change its viewing angle has highlighted the importance of modeling the atmospheric effects. So, atmospheric correction serves a critical role in the processing of remotely sensed image data, particularly with respect to identification of pixel content. Efficient and accurate realization of images in units...

The present 2 generation aerosol retrieval algorithm over oceans at NOAA/NESDIS separately retrieves two values of aerosol optical depth, 1 and 2, from AVHRR channels 1 and 2 centered at 1=0.63 (operational) and 2=0.83 μm (experimental), respectively. From these, an effective Angstrom exponent, , related to particle size, can be derived as =-ln( 1/ 2)/ln( 1/ 2). The single-channel look-up-table...

We describe a set of experiments that investigate diffusion of barium 6s5d DJ metastable level and 6s S0 ground-state atoms through the noble gases: He, Ne, Ar, Kr, and Xe. The barium metastable levels were populated through optical pumping of the 6s S0→6s6p P 1 intercombination transition with a pulsed laser, followed by spontaneous or stimulated emission into the 6s5d D1,2 levels. Collisional...

The leaf area index (LAI), a key parameter used to characterize the structure and function of vegetation canopy, is crucial simulations carbon, nitrogen, water cycles Earth’s system. In this paper, neural network (NN) method coupled with canopy atmospheric radiative transfer (RT) proposed realize LAI retrieval without prior data support complex corrections. look-up table (LUT) top-of-atmosphere...

GM1-gangliosidosis i s a n a utosomal r ecessive l ysosomal s torage disease, caused by deficiency of lysosomal β-galactosidase (β-gal), encoded by the GLB1 gene. To date, more than 160 human GLB1 gene mutations has been identified i n patients w ith t his disease, an d ab out 7 0% o f t hem ar e m issense mutations. C hemical ( or p harmacological) ch aperone t herapy h as b een developed a s ...