Imported animals, especially those from developing countries, may constitute a potential hazard to native animals and to public health. In this study, a new flock of lesser flamingos imported from Tanzania to Hiroshima Zoological Park were screened for multidrug-resistant Gram-negative bacteria, integrons and antimicrobial resistance genes. Thirty-seven Gram-negative bacterial isolates were obt...

Three major groups of the plasmid-mediated quinolone resistance (Qnr) determinants have been identified so far in Enterobacteriaceae: the QnrA group, which includes 6 variants, the QnrB group, which includes 19 variants, and the QnrS group, which includes 3 variants (5). Although Qnr proteins produce only low-level resistance, they provide a favorable background for higher resistance to occur a...

OBJECTIVES Pentapeptide repeat proteins (PRPs) QnrA, QnrB and QnrS confer reduced susceptibility to quinolones. This study presents an in vitro analysis of the genetic evolution of quinolone resistance mediated by changes in the coding sequences and promoter regions of qnrA1, qnrS1 and qnrB1 genes. METHODS A random mutagenesis technique was used to predict the evolutionary potential of these ...

OBJECTIVES To gain insight into the functionality of qnr-like genes of several bacterial species of Vibrionaceae that may encode quinolone resistance determinants. METHODS A PCR-based strategy was used to obtain qnr-like genes of reference strains of Vibrio vulnificus CIP103196, Vibrio parahaemolyticus CIP71.2 and Photobacterium profundum CIP106289 that were sequenced, cloned and expressed in...

The study aimed to investigate the occurrence of carbapenem resistant E. coli and P. aeruginosa in apparently healthy, captive blackbucks leopards India. Faecal samples (n = 7) were processed isolate (CRE) (CRP). Forty (leopards n 26; blackbuck 14) two (blackbuck 2) isolated from faecal 14). Eleven isolates recovered, which 10 CRE one was CRP. minimum inhibitory concentration (MIC) determined f...

Objective(s): Plasmid-mediated quinolone resistance (PMQR) determinants and integrons have a considerable contribution to bacterial drug resistance in Gram-negative pathogens. We studied the prevalence of PMQR genes and integron carriage in multidrug-resistant community isolates of Klebsiella spp.Materials and Methods: Two hundred and fi...