Background: Although the chemotherapeutic agents have been known for their cytotoxic effects on normal mammalian cells, these compounds are used widely for controlling the carcinogenic cells proliferation. Cyclophosphamide (CP), a well-known nitrogen mustard alkylating agent is used for autoimmune disorders and tumors treatment. Considering the inhibitory effect of CP on cell division, the ovar...

A bstract Solutions of the Strong CP Problem based on spontaneous breaking must feature a non-generic structure and simultaneously explain coincidence between priori unrelated CP-even CP-odd mass scales. We show that these properties can emerge from gauge invariance CP-conserving, but otherwise generic, physics at Planck scale. In our scenarios no fundamental scalar is introduced beyond Standar...

Objectives: To determine the role of child factors in the prediction of parental attitudes towards children and adolescents with CP in Iran. Methods: A cross-sectional study design was used. One hundred fifty-two children and adolescents with CP aged 7-17 years (mean = 10.93, SD = 3.46) with a mother aged at least 25 years were selected using systematic random sampling. The Mother-Child Relati...

Introduction: Cyclophosphamide (CP) is used for the treatment of various cancers. In spite of its therapeutic importance, a wide range of adverse effects such as reproductive toxicity has been observed following the administration of this drug in human and experimental animals. In the current study, we have investigated the adverse effects of CP on morphology and histology of testis rats. M...