Introduction: Collecting a patient’s pain scores and the analgesic effect achieved during spinal cord stimulation (SCS) trials can be difficult, and no standard exists for doing so. We propose a topographical mapping tool that was derived from a patient’s perspective. Case: A 60-year-old man with postherpetic neuralgia (PHN) underwent a SCS trial after conservative treatment failed to relieve h...

BACKGROUND The human anterior cruciate ligament (hACL) and medial collateral ligament (hMCL) of the knee joint are frequently injured, especially in athletic settings. It has been known that, while injuries to the MCL typically heal with conservative treatment, ACL injuries usually do not heal. As adult stem cells repair injured tissues through proliferation and differentiation, we hypothesized...

We continue the study of semicompact sets in a topological space. Several properties, mapping properties of semicompact sets are studied. A special interest to SCS spaces is given, where a space X is SCS if every subset of X which is semicompact in X is semiclosed; we study several properties of such spaces, it is mainly shown that a semi-T2 semicompact space is SCS if and only if it is extrema...

Spinal cord stimulation (SCS) is a valuable treatment for chronic intractable neuropathic pain. Although SCS has gone through a technological revolution over the last four decades, the neurophysiologic and biochemical mechanisms of action have only been partly elucidated. Animal experimental work has provided some evidence for spinal as well as supraspinal mechanisms of neuropathic pain relief ...

AIMS Epidural spinal cord stimulation (SCS) provides symptom relief in refractory angina pectoris, but its mechanism of action remains incompletely understood. We studied effects of short-term SCS therapy on myocardial ischaemia tolerance, myocardial perfusion reserve (MPR), and endothelium-mediated vasodilatation induced by cold pressor test (CPT) in patients with refractory angina pectoris. ...

BACKGROUND Psychological factors are recognised as influencing the outcome of spinal cord stimulation (SCS) although there is currently no consensus as to which factors impact upon SCS efficacy. OBJECTIVE To identify psychological characteristics that may impact the efficacy of SCS. STUDY DESIGN Prospective evaluation. SETTING Single secondary care center in Dudley, United Kingdom. METH...

OBJECTIVE To investigate the possibility that spinal cord stimulation (SCS) used for pain relief can conceal acute myocardial infarction (AMI). DESIGN Prospective evaluation of patients treated with SCS. SETTING University hospital. PATIENTS 50 patients with coronary artery disease and severe, otherwise intractable angina treated with SCS for 1-57 months. MAIN OUTCOME MEASURES Necropsy ...

OBJECTIVE Transplantation of bone marrow stromal cells (BMSCs) or Schwann cells (SCs) can facilitate axonal regeneration in peripheral nerve injuries. The aim of this study was to compare the effects of transplantation of BMSCs and SCs on functional recovery after injury to the sciatic nerve in the rat. MATERIALS AND METHODS In this experimental research, adult male Wistar rats (n=24, 250-300...

The objective of this study was to develop a method for calculating economic values of clinical mastitis (CM) and somatic cell score (SCS) for inclusion in a dairy cattle breeding goal in the context of a country where farm production and economic data are scarce. In order to calculate the costs and derive economic values for SCS, a new model, 'milk collection method', has been developed and wa...