Software processes improvement (SPI) is a challenging task, as many different stakeholders, project settings, and contexts and goals need to be considered. SPI projects are often operated in a complex and volatile environment and, thus, require a sound management that is resource-intensive requiring many stakeholders to contribute to the process assessment, analysis, design, realisation, and de...

The present study investigated the effect of dietary soy protein isolate (SPI) on tumor necrosis factor-alpha (TNF) productivity in peritoneal macrophages from nephritic and hepatoma-bearing rats. Dietary SPI significantly inhibited the elevated production of TNF by lipopolysaccharide-stimulated macrophages in nephritic and hepatoma-bearing rats compared with dietary casein, while it exerted no...

While software process improvement is well established as a practice, it still presents challenges for some adopters. Drop-outs from SPI programs are not uncommon. The paper argues that SPI sustainment is a function of the organizational context of the program, not just of the program (or SPI ‘product’) itself. Critical in this context is the organization’s operational capabilities and capacity...

BACKGROUND Three pathogenicity islands, viz. SPI-1 (Salmonella pathogenicity island 1), SPI-2 (Salmonella pathogenicity island 2) and T6SS (Type VI Secretion System), present in the genome of Salmonella typhimurium have been implicated in the virulence of the pathogen. While the regulation of SPI-1 and SPI-2 (both encoding components of the Type III Secretion System - T3SS) are well understood,...

The prevailing paradigm of Salmonella enteropathogenesis based on monolayers asserts that Salmonella pathogenicity island-1 Type Three Secretion System (SPI-1 T3SS) is required for bacterial invasion into intestinal epithelium. However, little is known about the role of SPI-1 in mediating gastrointestinal disease in humans. Recently, SPI-1 deficient nontyphoidal Salmonella strains were isolated...

In recent years a substantial number of organizations have gained experience in software process improvement (SPI). Furthermore, some researchers have studied such organizations by collecting and analyzing costs and benefits data on their SPI efforts. The objective of this report is to review and summarize the empirical evidence thus far on the costs and benefits of SPI. The intention is that t...

Software process improvement (SPI) approaches have been designed to produce changes at many levels, i.e. in the strategies, culture and working practices, of software development. Studies have shown that nearly two thirds of all SPI efforts have failed or fallen short of expectations. It is often stated in SPI-related literature and practice that "commitment" to SPI plays an important part in d...

Soy protein isolate (SPI) in the diet may inhibit colon tumorigenesis. We examined azoxymethane (AOM)-induced aberrant crypt foci (ACF) in male rats in relation to lifetime, pre-weaning, or post-weaning dietary exposure to SPI and also within the context of fetal alcohol exposure. Pregnant Sprague Dawley rats were fed AIN-93G diets containing casein (20%, the control diet) or SPI (20%) as the s...

In an assessment of software process improvement (SPI) in 15 software smalland –medium-sized enterprises (software SMEs), we applied the broad spectrum of software specific and system context processes in ISO/IEC 12207 to the task of examining SPI in practice. Using the data collected in the study, we developed a four-tiered pyramidal hierarchy of SPI for software SMEs, with processes in the hi...

The Capability Maturity Model Integration (CMMI) is a structured representation of software development processes that can support an organisation’s software process improvement (SPI) strategies. However, CMMI and SPI initiatives generally exhibit low levels of adoption and limited success. One of the major reasons for these shortcomings is that many organisations undertake SPI initiatives with...