INTRODUCTION This article discusses the process of defining competencies and development of a best practices training course for investigators and clinical research coordinators who conduct social and behavioral research. METHODS The first project phase established recommendations for training in Good Clinical Practice (GCP) and was done in conjunction with representatives from 62 Clinical an...

Wireless sensor networks (WSN) have recently received an increasing interest. They are now expected to be deployed for long periods of time, thus requiring software updates. Updating the software code automatically on a huge number of sensors is a challenging task, especially when all participating sensors are embedded on mobile entities. In this paper, we investigate an approach to automatical...

The clinical research industry is one of the most heavily regulated industries that exists. One cannot function in this industry in a compliant manner without knowing the regulations and the responsibilities they are expected to maintain. Good Clinical Practice (GCP) is a set of guidelines for the design, performance, monitoring, recording, analysis, and reporting of clinical trials. Only by ma...

Graph Coloring Problem (GCP) bears an enormous significance to the researchers in the field of soft computing. In this paper, we demonstrate a Quantum-Inspired Evolutionary Algorithm (QEA) to solve GCP. We use two dimensional arrays of Q-bits called Q-bit individual to produce binary individual. Q-gate operation is applied as a variation operator on Q-bit individuals. In traditional evolutionar...

Glutamate carboxypeptidase II (GCP II) is a therapeutic target in neurologic disorders associated with excessive activation of glutamatergic systems. The potent, orally bioavailable GCP II inhibitor 2-(3-mercaptopropyl) pentanedioic acid (2-MPPA) is effective in preclinical models of diseases where excess glutamate release is implicated, including neuropathic pain, and was the first GCP II inhi...

Cam contour fitting is greatly affected by data segmentation errors. Yet traditional methods are susceptible to noise and not able cope with of multiple curve type. Therefore, a new method proposed based on Generalized Cross Product (GCP), the arc cam taken as examples. Regarding series fragments, circular features each fragment transformed GCP norm vector mapping. Based robustness GCP, disturb...

Cultured guard cell protoplasts (GCP) of tree tobacco (Nicotiana glauca) comprise a novel system for investigating the cell signaling mechanisms that lead to acquired thermotolerance and thermoinhibition. At 32 degrees C in a medium containing an auxin (1-naphthaleneacetic acid [NAA]) and a cytokinin (6-benzylaminopurine), GCP expand, regenerate cell walls, dedifferentiate, and divide. At 38 de...

Folding of the cortex and the persistence of radial glia (RG)-like cells called Bergmann glia (BG) are hallmarks of the mammalian cerebellum. Similar to basal RG in the embryonic neocortex, BG maintain only basal processes and continuously express neural stem cell markers. Past studies had focused on the function of BG in granule cell migration and how granule cell progenitors (GCP) regulate ce...

This paper is focused on the use of Zero Moment Point (ZMP) concept for balancing control of the Asian Institute of Technology Leg EXoskeleton-I (ALEX-I). ALEX-I has been developed to assist patients who suffer from paraplegia or immobility due to the loss of power on lower limbs. The balanced posture set-points (joint trajectories) under ZMP criterion are generated offline. The ZMP based set p...

BACKGROUND Cognitive impairment is a well-recognized risk factor for delirium. Our goal was to determine whether the level of cognitive performance across the nondemented cognitive ability spectrum is correlated with delirium risk and to gauge the importance of cognition relative to other known risk factors for delirium. METHODS The Successful Aging after Elective Surgery study enrolled 566 a...