INTRODUCTION Classically, the monocytic component of acute myelomonocytic (FAB-M4) and acute monocytic/monoblastic (FAB-M5) leukemias is demonstrated by nonspecific esterase positivity in cytochemical stainings. We have previously demonstrated that non-specific esterases from normal monocytes can be determined by a chemiluminescent method. In the present study, we investigated whether this assa...

PURPOSE To investigate the expression of the muscarinic receptor (mAChR) subtypes (m1, m2, m3, m4, and m5) in the human ciliary muscle. METHODS cDNA probes specific for the m1 to m5 subtypes were used to characterize the expression of subtype-specific mRNAs by in situ hybridization and Northern blot analysis on a cell line derived from human ciliary muscle tissue (H7CM), sectioned tissue from...

We consider world-volume description of M2-branes ending on an M5-brane. The system can be described either as a solitonic solution of the M5-brane field equations or in terms of an effective string propagating in 6-dimensions. We show that the zeroth order scalar scattering amplitudes behave similarly in both pictures. The soliton solution appears to have a horizon-like throat region. Due to t...

By using O(7, 7) transformations, to deform D6–branes, we obtain half-supersymmetric bound state solutions of type IIA supergravity, containing D6, D4, D2, D0, F1-branes and waves. We lift the solutions to M-theory which gives half-supersymmetric M-theory bound states, e.g. KK6–M5–M5–M5–M2–M2–M2–MW. We also take near horizon limits for the type IIA solutions, which gives supergravity duals of 7...

The role of endophytic fungi in plant growth and development is well documented. However, endophytic fungi with growth promotion capacity have never been isolated from weeds previously. In the current study, we isolated 8 fungal endophytes from the roots of Monochoria vaginalis, a serious weed of rice paddy in Korea. These isolates were screened on Waito-C, in order to identify plant growth pro...

Myosin V is a double-headed unconventional myosin that has been implicated in organelle transport. To perform this role, myosin V may have a high duty cycle. To test this hypothesis and understand the properties of this molecule at the molecular level, we used the laser trap and in vitro motility assay to characterize the mechanics of heavy meromyosin-like fragments of myosin V (M5(HMM)) expres...

Patients with NPM1-mutated AML M5 who develop spontaneous remission (SR) after antibiotic therapy at diagnosis seem to form a favorable prognosis and chemo sensitive subtype. We report three cases of AML M5 patients with the same genotype that experienced transient SR and are now leukemia free after standard treatment.

A xenogeneic rat anti-mouse la monoclonal antibody, M5/114 ( y P b , ~ ) , was studied for its effects in vitro on T cell proliferative responses. Strain distribution studies revealed that M5/114 could inhibit I-A subregion-restricted T cell responses of the H-2btd.qtU but not the H2'-**" haplotypes, indicating that this xenoantibody recognizes a polymorphic determinant on mouse la molecules....

T-cell molecular mimicry between streptococcal and heart proteins has been proposed as the triggering factor leading to autoimmunity in rheumatic heart disease (RHD). We searched for immunodominant T-cell M5 epitopes among RHD patients with defined clinical outcomes and compared the T-cell reactivities of peripheral blood and intralesional T cells from patients with severe RHD. The role of HLA ...