OBJECTIVES This work deals with the conformational and thermal characterization of a synthetic peptide (S4) released during the proteolysis of human tropoelastin by the matrix metalloproteinase-12 that was shown to form amyloid-like fibres under certain conditions. MATERIALS AND METHODS S4 peptides were synthesized by solid-phase methodology and aggregated in solution at 80°C. Fourier transfo...

BACKGROUND This study was to elucidate the psychometric properties of the Korean version of the Diabetes Symptom Checklist-Revised (K-DSC-R), which is a patient-reported outcome measure of diabetes symptom burden. METHODS A sample of 432 Korean patients with diabetes was recruited from university hospitals. The data were analyzed using exploratory factor analysis (EFA), confirmatory factor an...

We have previously reported that the danshensu-cysteine conjugate N-((R)-3-benzylthio-1-methoxy-1-oxo-2-propanyl)-2-acetoxy-3-(3,4-diacetoxyphenyl) propanamide (DSC) is a potent anti-oxidative and anti-apoptotic agent. Herein, we further design and asymmetrically synthesize two diastereoisomers of DSC and explore their potential bioactivities. Our results show that DSC and its two diastereoisom...

Mesenchymal stromal cells (MSCs) are increasingly used in regenerate medicine. Placenta-derived decidual stromal cells (DSCs) are a novel therapy for acute graft-versus-host-disease (GVHD) and hemorrhagic cystitis (HC) after allogeneic hematopoietic stem cell transplantation (HSCT). DSCs are more immunosuppressive than MSCs. We assessed adverse events and safety using DSCs among 44 treated pati...

The methods of measuring the heat capacity of materials by differential scanning calorimetry (DSC) are presented and discussed. The principles of temperature modulated DSC are outlined and the possibilities and limits of the method are discussed.

رابطه‌­ی شدت ترمولومینسانس براساس مدل سینتیک مرتبه‌­ی اول بدون در نظرگرفتن اثر فروکشی دمایی مورد استفاده قرار می‌­گیرد. این حالی است که به عنوان یک واقعیت فیزیکی باید روابط بیان‌­کننده‌­ی توجه گیرد. کار با نظر گرفتن برای اول، تابع جداسازی منحنی تابش جدیدی برحسب و دمای قله دست آمد. نحوی جدید حذف مشخصه‌­های دمایی، همان قبلی خود تبدیل می‌­شود. دزیمتر (400TLD-) :Mn2CaF بررسی گرفت. این‌­که ­شدت طبق ...

This communication introduces a novel scheme for the treatment of free edge supports in the analysis of beams by using the discrete singular convolution (DSC) algorithm. Accommodating free edges has been a challenging issue in the DSC analysis of beams, plates, and shells. An iteratively matched boundary (IMB) method is proposed to overcome the difficulty. Numerical experiments are carried out ...

Extrinsic and intrinsic characterizations are given for the class DSC(K) of differences of semi-continuous functions on a Polish space K, and also decomposition characterizations of DSC(K) and the class PS(K) of pointwise stabilizing functions on K are obtained in terms of behavior restricted to ambiguous sets. The main, extrinsic characterization is given in terms of behavior restricted to som...

The deep superior colliculus (DSC) integrates multisensory input and triggers an orienting movement toward the source of stimulation (target). It would seem reasonable to suppose that input of an additional modality should always increase the amount of information received by a DSC neuron concerning a target. However, of all DSC neurons studied, only about one half in the cat and one-quarter in...