Starritt, Emma C., Richard A. Howlett, George J. F. Heigenhauser, and Lawrence L. Spriet. Sensitivity of CPT I to malonyl-CoA in trained and untrained human skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 278: E462–E468, 2000.—The present study examined the sensitivity of carnitine palmitoyltransferase I (CPT I) activity to its inhibitor malonyl-CoA (M-CoA), and simulated metabolic conditio...

YUKO YAMBE,1 YASUKO WATANABE-TOMITA,1 SATOSHI KAKIYA,1 HISASHI YOKOI,1 HIROSHI NAGASAKI,1 HIROSHI ARIMA,1 TAKASHI MURASE,1 HIROMITSU YUASA,1,2 KUNIKAZU KONDO,1,3 HIROSHI YAMASHITA,4 AND YUTAKA OISO1 1First Department of Internal Medicine, Nagoya University School of Medicine, Nagoya 466–8550; 2Nagoya Higashi Municipal Hospital, Nagoya 464–0071; 3Anjo Kosei Hospital, Anjo 446–8602; and 4First De...

König, Jörg, Yunhai Cui, Anne T. Nies, and Dietrich Keppler. A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane. Am. J. Physiol. Gastrointest. Liver Physiol. 278: G156–G164, 2000.—We cloned and expressed a new organic anion transporting polypeptide (OATP), termed human OATP2, (OATP-C, LST-1; symbol SLC21A6), involved in the uptake of various li...

Simaan, May, Serge Picard, Jean St-Louis and Michèle Brochu. Functional alteration of dihydropyridinesensitive Ca21 channels in the adrenal glomerulosa of pregnant rats. Am J Physiol Endocrinol Metab 278: E925–E932, 2000.—Our previous work on aldosterone secretion suggested that dihydropyridine-sensitive calcium channels, one type of voltage-dependent calcium channels (VDCC), are functionally i...

Pausawasdi, N., S. Ramamoorthy, V. Stepan, J. Del Valle, and A. Todisco. Regulation and function of p38 protein kinase in isolated canine gastric parietal cells. Am. J. Physiol. Gastrointest. Liver Physiol. 278: G24–G31, 2000.—We examined the regulation and functional role of p38 kinase in gastric acid secretion. p38 kinase was immunoprecipitated from cell lysates of highly purified gastric par...

Hilton, L. K., and A. B. Loucks. Low energy availability, not exercise stress, suppresses the diurnal rhythm of leptin in healthy young women. Am. J. Physiol. Endocrinol. Metab. 278: E43–E49, 2000.—Because the effect of exercise on leptin was not established, we controlled energy intake (I) and exercise energy expenditure (E) to distinguish the independent effects of energy availability (A 5 I ...

Kuemmerle, John F. Endogenous IGF-I regulates IGF binding protein production in human intestinal smooth muscle cells. Am J Physiol Gastrointest Liver Physiol 278: G710– G717, 2000.—Human intestinal smooth muscle in culture produces insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-3, IGFBP-4, and IGFBP-5, which modulate the effects of IGF-I. This study examined the regulation o...