نتایج جستجو برای: مدل gep

تعداد نتایج: 121158  

2017
Meng Zhang Ping Zhao Xiaodan Shi Ahong Zhao Lianfeng Zhang Lin Zhou

BACKGROUND Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are the most common type of neuroendocrine tumors, accounting for more than half of neuroendocrine neoplasms (NENs). We performed a retrospective study in our center to investigate the clinicopathological features, risk factors of metastasis, and prognosis of GEP-NENs in a Chinese population. METHODS Four hundred forty pati...

Journal: :BMC endocrine disorders 2016
Doris T Chan Andrea O Y Luk W Y So Alice P S Kong Francis C C Chow Ronald C W Ma Anthony W I Lo

BACKGROUND There is rising incidence of gastroenteropancreatic neuroendocrine tumours (GEP- NETs) in many parts of the world, but epidemiological data from Asian populations is rare. METHODS We conducted a retrospective study in a tertiary medical centre in Hong Kong, using updated diagnostic criteria. The presentation, clinical features, and disease outcome were reviewed for all patients wit...

ژورنال: محیط شناسی 2017

هدف از تحقیق حاضر مدل‌سازی توزیع آرسنیک در دشت چهاردولی با استفاده از زمین‌آمار، منطق فازی و برنامه‌ریزی بیان ژنتیک (GEP) می‌باشد. بدین منظور گروه زمین‌شناسی دانشگاه تبریز در مهر 1393 اقدام به نمونه‌برداری از منابع آب زیرزمینی این دشت نمود. که نتایج حاصل حاکی از غلظت‌های بالای آرسنیک در منطقه می‌باشد. پارامترهای هیدروشیمیایی شامل آرسنیک و سیلیس، پتاسیم و سدیم که همبستگی بالایی با مقادیر آرسنیک ...

2008
Giancarlo Bigi Marco Castellani Gábor Kassay

The aim of this paper is to introduce and study a dual problem associated to a generalized equilibrium problem (GEP). We show that the solutions of (GEP) and its dual are strictly related to the saddle points of an associated Lagrangian function, and, under some suitable conditions, to the solutions of a family of parametric optimization problems and their dual problems. Our results allow us to...

Journal: :Current oncology 2017
M A O'Brien S Dhesy-Thind C Charles M Hammond Mobilio N B Leighl E Grunfeld

PURPOSE Advances in personalized medicine have produced novel tests and treatment options for women with breast cancer. Relatively little is known about the process by which such tests are adopted into oncology practice. The objectives of the present study were to understand the experiences of medical oncologists with multigene expression profile (gep) tests, including their adoption into pract...

2003
Monica Brown Jones Chad M. Michener James O. Blanchette Vladimir A. Kuznetsov Mark Raffeld Ginette Serrero Michael R. Emmert-Buck Emanuel F. Petricoin David B. Krizman Lance A. Liotta Elise C. Kohn

Purpose: The role of growth factors in ovarian cancer development and progression is complex and multifactorial. We hypothesized that new growth factors may be identified through the molecular analysis of ovarian tumors as they exist in their native environment. Experimental Design: RNA extracted from microdissected serous low malignant potential (LMP) and invasive ovarian tumors was used to co...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2011
Tobias Meissner Anja Seckinger Thierry Rème Thomas Hielscher Thomas Möhler Kai Neben Hartmut Goldschmidt Bernard Klein Dirk Hose

PURPOSE Multiple myeloma is an incurable malignant plasma cell disease characterized by survival ranging from several months to more than 15 years. Assessment of risk and underlying molecular heterogeneity can be excellently done by gene expression profiling (GEP), but its way into clinical routine is hampered by the lack of an appropriate reporting tool and the integration with other prognosti...

2012
Benjamin N. Sulman Ankur R. Desai Nicole M. Schroeder Dan Ricciuto Alan Barr Andrew D. Richardson Lawrence B. Flanagan Peter M. Lafleur Hanqin Tian Guangsheng Chen Robert F. Grant Benjamin Poulter Hans Verbeeck Philippe Ciais Bruno Ringeval Ian T. Baker Kevin Schaefer Yiqi Luo Ensheng Weng

[1] Northern peatlands are likely to be important in future carbon cycle-climate feedbacks due to their large carbon pools and vulnerability to hydrological change. Use of non-peatland-specific models could lead to bias in modeling studies of peatland-rich regions. Here, seven ecosystem models were used to simulate CO2 fluxes at three wetland sites in Canada and the northern United States, incl...

2012
Mee-Yon Cho Joon Mee Kim Jin Hee Sohn Mi-Jung Kim Kyoung-Mee Kim Woo Ho Kim Hyunki Kim Myeong-Cherl Kook Do Youn Park Jae Hyuk Lee HeeKyung Chang Eun Sun Jung Hee Kyung Kim So-Young Jin Joon Hyuk Choi Mi Jin Gu Sujin Kim Mi Seon Kang Chang Ho Cho Moon-Il Park Yun Kyung Kang Youn Wha Kim Sun Och Yoon Han Ik Bae Mee Joo Woo Sung Moon Dae Young Kang Sei Jin Chang

PURPOSE As a result of various independently proposed nomenclatures and classifications, there is confusion in the diagnosis and prediction of biological behavior of gastroenteropancreatic neuroendocrine tumors (GEP-NETs). A comprehensive nationwide study is needed in order to understand the biological characteristics of GEP-NETs in Korea. MATERIALS AND METHODS We collected 4,951 pathology re...

2017
María Laura Gutiérrez Luis Antonio Corchete María Eugenia Sarasquete María del Mar Abad Oscar Bengoechea Encarna Fermiñán María Fernanda Anduaga Sofía del Carmen Manuel Iglesias Carmen Esteban María Angoso Jose Antonio Alcazar Jacinto García Alberto Orfao Luis Muñoz-Bellvís José María Sayagués

Despite significant advances have been achieved in the genetic characterization of sporadic colorectal cancer (sCRC), the precise genetic events leading to the development of distant metastasis remain poorly understood. Thus, accurate prediction of metastatic disease in newly-diagnosed sCRC patients remains a challenge. Here, we evaluated the specific genes and molecular pathways associated wit...

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