1Department of Cardiovascular Medicine, 2Translational Systems Biology and Medicine Initiative, 3Computational Diagnostic Radiology and Preventive Medicine, 4Department of Diabetes and Metabolic Diseases, The University of Tokyo, Tokyo 113-8654, Japan 5Center for Molecular Medicine, Jichi Medical University, Tochigi 329-0498, Japan 6Japan Science and Technology Agency (JST), Precursory Research...

1 Department of Neurology, School of Medicine, Oregon Health and Science University, Portland, OR 97239, USA 2 Department of Psychology and Communication Studies, University of Idaho, Moscow, ID 83844-3043, USA 3 Department of Behavioural Neuroscience, School of Medicine, Oregon Health and Science University, Portland, OR 97239, USA 4 Department of Psychiatry, School of Medicine, Oregon Health ...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 205 No. 1 83–96 www.jcb.org/cgi/doi/10.1083/jcb.201311104 JCB 83 Correspondence to Jennifer Lippincott-Schwartz: [email protected] Dylan T. Burnette’s present address is Dept. of Cell and Developmental Biology, Vanderbilt Medical Center, Nashville, TN 37232. Abbreviations used in this paper: DSF, dorsal stress fiber; MEF, mouse embr...

Neurogenesis involves deeply conserved patterning molecules, such as the proneural basic helix-loop-helix transcription factors. Sox proteins and specifically members of the SoxB and SoxC groups are anotherclassof conserved transcription factorswithan important role in neuronal fate commitment and differentiation in various species. In this study,we examine the expressionof all fiveSox genes of...

Methods and Results-—We investigated whether dietary salt restriction might ameliorate cardiac injury in DahlS.Z-Lepr/Lepr (DS/obese) rats, which are derived from a cross between Dahl salt-sensitive and Zucker rats and represent a model of metabolic syndrome. DS/obese rats were fed a normal-salt (0.36% NaCl in chow) or low-salt (0.0466% NaCl in chow) diet from 9 weeks of age and were compared w...

1 Department of Neurology and Institute of Molecular Medicine and Genetics, Medical College of Georgia, Georgia Regents University, Augusta, GA 30912, USA 2 Neurobiology Institute of Medical Research Centre, Hebei United University, 57 South Jian-she Road, Tangshan, Hebei, 063000, PR China 3 Department of Obstetrics and Gynecology, University of Texas Health Science Centre at San Antonio, Floyd...

12 In diversity research, the use of survey data appears to have declined in favour of experimental or modeling 13 approaches because direct relationships are difficult to demonstrate. Here we show that use of field data can 14 yield information concerning the mechanisms governing diversity. First, we establish that tintinnids display 15 a global latitudinal pattern of diversity similar to othe...

The transcription factor forkhead box P2 (FOXP2) is believed to be important in the evolution of human speech. A mutation in its DNA-binding domain causes severe speech impairment. Humans have acquired two coding changes relative to the conserved mammalian sequence. Despite intense interest in FOXP2, it has remained an open question whether the human protein’s DNAbinding specificity and chromat...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 208 No. 4 401–414 www.jcb.org/cgi/doi/10.1083/jcb.201410105 JCB 401 *J.E. Klebba and B.J. Galletta contributed equally to this paper. **N.M. Rusan and G.C. Rogers contributed equally to this paper. Correspondence to Nasser M. Rusan: [email protected]; or Gregory C. Rogers: [email protected] Abbreviations used in this paper: ...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 208 No. 7 961–974 www.jcb.org/cgi/doi/10.1083/jcb.201410095 JCB 961 Correspondence to Rati Fotedar: [email protected] Dr. Arun Fotedar died on 9 July 2007. Abbreviations used in this paper: ANOVA, analysis of variance; CB, cytoskeletal buffer; CCD, charge-coupled device; CMV, cytomegalovirus; DIC, differential interference con...