OBJECTIVE This study examined effects of transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) and orbitofrontal cortex (OFC) on major executive functions (EFs), including response inhibition, executive control, working memory (WM), and cognitive flexibility/task switching in ADHD. METHOD ADHD children received (a) left anodal/right cathodal DLPFC tDCS...

When tracking visible or occluded moving targets, several frontal regions including the frontal eye fields (FEF), dorsal-lateral prefrontal cortex (DLPFC), and anterior cingulate cortex (ACC) are involved in smooth pursuit eye movements (SPEM). To investigate how these areas play different roles in predicting future locations of moving targets, 12 healthy college students participated in a smoo...

Abstract Repetitive transcranial magnetic stimulation (rTMS) is a clinically effective treatment in major depressive disorder (MDD) when targeting the dorsolateral prefrontal cortex (DLPFC). Yet, at least 44% of patients do not achieve remission, requiring validated alternatives, such as orbitofrontal (OFC) targeted rTMS. Preliminary results employing 1Hz OFC-rTMS show 30% achieving response (i...

BACKGROUND Two brain regions often implicated in schizophrenia are the dorsolateral prefrontal cortex (DLPFC) and the hippocampal formation (HF). It has been hypothesized that the pathophysiology of the disorder might involve an alteration of functional interactions between medial temporal and prefrontal areas. METHODS We used neuroimaging data acquired during a working memory challenge and a...

OBJECTIVE To assess whether multifocal, high-frequency repetitive transcranial magnetic stimulation (rTMS) of motor and prefrontal cortex benefits motor and mood symptoms in patients with Parkinson disease (PD). METHODS Patients with PD and depression were enrolled in this multicenter, double-blind, sham-controlled, parallel-group study of real or realistic (electric) sham rTMS. Patients were...

AbstractBackground High-frequency rTMS over the dorsolateral prefrontal cortex (DLPFC) has demonstrated mixed effects on chronic and provoked pain. Objectives/Methods In this study, a meta-analysis was conducted to characterise potential analgesic of high-frequency DLPFC both Results A total 626 studies were identified in systematic search. Twenty-six eligibl...

BACKGROUND The difficulty in treating mood disorders has brought about clinical interest in alternative treatments, such as transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (DLPFC). However, the optimal parameters for stimulation and underlying mechanisms of action are unclear. Psychiatric treatments have acute effects on emotional processing that predict lat...