The Harmonic Excitation Linear Predictive Speech Coder (HE-LPC) is a technique derived from MBE [1] and MBLPC [2] type of speech coding algorithms. The HE-LPC coder has the potential of producing high quality speech at 4.8 kb/s and below. This coder employs a new pitch estimation and voicing technique. In addition, new DCT based LPC and residual amplitude quantization techniques have been devel...

A power-weighted formant frequency estimation procedure based on Linear Predictive Coding (LPC) is presented. It works by pre-emphasizing the dominant spectral components of an input signal, which allows a subsequent step to extract frequencies with greater accuracy. The accuracy traditional LPC improved this new estimator for different classes synthetic signals and speech. Power-weighted signi...

The idea of applying vector quantization (VQ) to linear prediction coding (LPC) to realize a very low bit-rate speech coder with reasonable speech quality is investigated in this research. Instead of encoding LPC parameters directly, line spectral frequency (LSF) coefficients are obtained through a transformation of LPC and then encoded via VQ in the proposed scheme. In order to utilize the int...

The P2X7 receptor (P2X7R), an ATP-gated ion channel, plays essential roles in the release and maturation of IL-1beta in microglial cells in the brain. Previously, we found that lysophosphatidylcholine (LPC) potentiated P2X7R-mediated intracellular signals in microglial cells. In this study, we determined whether the lysophospholipids, i.e., LPC and sphingosylphosphorylcholine (SPC), modulate th...

A highly e cient algorithm termed adaptive forward-backward vector quantization (AFBVQ) is developed for variable bit rate quantization of linear predictive coding (LPC) coe cients and integrated with the FS1016 Federal Standard Code Excited Linear Predictive (CELP) coder. This results in a high performance low bit rate speech coder called as AFBVQCELP which brings in two-fold bit rate reductio...

OBJECTIVES Inhibitors of uridine diphosphate-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC, which catalyses the first, irreversible step in lipid A biosynthesis) are a promising new class of antibiotics against Gram-negative bacteria. The objectives of the present study were to: (i) compare the antibiotic activities of three LpxC inhibitors (LPC-058, LPC-011 and LPC-087) and ...

It is well-known that, within ERP paradigms of sentence processing, semantically anomalous words elicit N400 effects. Less clear, however, is what happens after the N400. In some cases N400 effects are followed by Late Positive Complexes (LPC), whereas in other cases such effects are lacking. We investigated several factors which could affect the LPC, such as contextual constraint, inter-indivi...

This paper describes a new speech analysis method, an adaptive Mel-LPC (AMLPC) analysis method, using human auditory characteristics. The Mel-LPC analysis method that we have proposed is an efficient time domain technique to estimate the warped predictors from input speech directly. However, the frequency resolution of spectrum obtained by Mel-LPC analysis is constant regardless of the characte...

The accretion of ice in the compression system of commercial gas turbine engines operating in high ice water content conditions is a safety issue being studied by the aviation community. While most of the research focuses on the underlying physics of ice accretion and the meteorological conditions in which accretion can occur, a systems-level perspective on the topic lends itself to potential n...

Although under some conditions the attention-related late positive event-related potential (ERP) response (LPC) is apparently normal in autism during visual processing, the LPC elicited by visuospatial processing may be compromised. Results from this study provide evidence for abnormalities in autism in two components of the LPC generated during spatial processing. The early frontal distributio...