Depression, anxiety, and behavioral health impairment are common in the US. Efforts to treat patients with depression, anxiety, and chemical dependency are surpassed by the great demand for psychiatrist and therapist appointments. Unlike other specialties, psychiatry lacks a vital sign or tests (eg, blood pressure for hypertension and hemoglobin A1c for diabetes) to objectively measure a patien...

Adriamycin (ADR) is a potent anticancer drug, but its use is limited by a dose-dependent cardiotoxicity. Oxidative stress is regarded as the mediating mechanism of ADR cardiotoxicity. However, cardiac proteins that are oxidatively modified have not been well characterized. We took a redox proteomics approach to identify increasingly oxidized murine cardiac proteins after a single injection of A...

A Tn5 mutant strain of Sinorhizobium meliloti with an insertion in tpiA (systematic identifier SMc01023), a putative triose phosphate isomerase (TPI)-encoding gene, was isolated. The tpiA mutant grew more slowly than the wild type on rhamnose and did not grow with glycerol as a sole carbon source. The genome of S. meliloti wild-type Rm1021 contains a second predicted TPI-encoding gene, tpiB (SM...

In this study, we aimed to evaluate the protein expression profile of a spectrum of renal cell carcinomas (RCC) to find potential biomarkers for disease onset and progression and therefore, prospective therapeutic targets. A 2D-gel based proteomic analysis was used to outline differences in protein levels among different subtypes of renal cell carcinomas, including clear cell carcinomas, papill...

The enzyme triosephosphate isomerase (TPI, EC 5.3.1.1) was purified from extracts of epimastigote forms of Trypanosoma cruzi. The purification steps included: hydrophobic interaction chromatography on phenyl-Sepharose, CM-Sepharose, and high performance liquid gel filtration chromatography. The CM-Sepharose material contained two bands (27 and 25 kDa) with similar isoelectric points (pI 9.3-9.5...

Introduction : Le paludisme pendant la grossesse représente un problème de santé publique majeur, avec des risques élevés pour mère, le fœtus et nouveau-né. L’Organisation Mondiale Santé recommande calendrier d'au moins quatre consultations prénatales lors grossesse. Notre étude s’est fixé ainsi l’objectif d’analyser rôle matrones dans TPI en milieu rurale Sélingué au Mali. Matériels méthodes N...

The Treponema pallidum haemagglutination (TPHA) test, the latest to be developed in the group of specific tests for syphilis, has been described by Tomizawa and Kasamatsu (1966), Rathlev (1967), Tomizawa, Kasamatsu, and Yamaya (1969), and Tringali (1970.) An automated microhaemagglutination technique, the AMHA-Tp test, has been evaluated by Cox, Logan, and Norins (1969) and Logan and Cox (1970)...

OBJECTIVE To investigate the effect of extracorporeal shock wave therapy (ESWT) on myofascial pain syndrome (MPS). METHOD Thirty patients with MPS in trapezius muscle were randomly divided into two groups, ESWT group (n=15), and trigger point injections (TPI)+transcutaneous electrical nerve stimulation (TENS) group (n=15). For a total of 3 weeks, ESWT was undertaken with 1,500 pulse each time...

We have previously shown that B cells and Abs reactive with GAPDH and antitriosephosphate isomerase (TPI) are present in lesions and cerebrospinal fluid (CSF) in multiple sclerosis (MS). In the current study, we studied the effect of anti-GAPDH and anti-TPI CSF IgG on the glycolytic enzyme activity of GAPDH and TPI after exposure to intrathecal IgG from 10 patients with MS and 34 patients with ...