EG-1 is significantly elevated in breast, colorectal, and prostate cancers. Overexpression of EG-1 stimulates cellular proliferation, and targeted inhibition blocks mouse xenograft tumor growth. To further clarify the function of EG-1, we investigated its role in c-Src activation. We observed that EG-1 overexpression results in activation of c-Src, but found no evidence that EG-1 is a direct Sr...

Massive blood loss resulting in hemorrhagic shock requires the use of a hemostatic tourniquet. According to literary sourced using tourniquet for 2 hours is safe, but newest investigations have shown ambiguous consequences body, coused by both local changes tissues under tourniquet’s pressure, and outflow metabolic products into general bloodstream from primarly ischemic limb.The aim was identi...