Perspectives Zika virus disease is caused by a ri-bonucleic acid (RNA) virus, which is transmitted to humans by mosquitoes of the Aedes aegypti species. Around 80% of infections are asymptomatic. 1 Symptomatic infections are characterized by mild fever lasting from four to seven days, associated with maculopapular rash, arthralgia, conjunctivitis, muscle pain and headache. Until recently, Zika ...

Although generally a sporadic disease, a few cases of Guillain Barre syndrome clustered in families have been reported. We describe four siblings of a Pakistani family from a consanguineous marriage out of whom two developed definite GBS and two had probable GBS at different times. This suggests that there may be a genetic element in the pathogenesis of at least some forms of Guillain Barre syn...

Restless Legs Syndrome (RLS) is a sleep-associated movement disorder with sensory and motor components that follows a chronic course. Acute development of RLS has rarely been reported. Our purpose was to raise awareness of the subject by describing a picture of acute RLS in a case of Guillain-Barre syndrome. Citation: Vildan Altunayoglu Cakmak., et al. “Restless Legs Syndrome Presenting As Acut...

Three patients with acute Guillain-Barré syndrome were treated early in the course of the disease with OKT3, an anti-T-cell monoclonal antibody. Each patient developed acute lymphopenia with specific depletion of T3-positive lymphocytes. Two patients had continued progression of clinical deficits for eight and 14 days. This suggests that T lymphocytes may not be essential for progression of Gui...

Bilateral facial nerve paralysis, as compared to unilateral palsyis an extremely rare presentation with serious aetiologies including post infectious like in Guillain-Barre syndrome, infectious including Lyme disease, Infectious Mononucleosis, autoimmune, malignancy (leukaemia) and traumas. We present a rare case of bilateral facial paralysis due to Guillain-Barré syndrome which was successfull...

Acute pandysautonomia has been suggested to be an uncommon variant of Guillain-Barre syndrome. Acute pandysautonomia does not seem to have been treated with intravenous immunoglobulin or other therapies proved efficacious in Guillain-Barre syndrome. A patient is reported with severe acute pandysautonomia who responded dramatically to intravenous immunoglobulin. The findings are consistent with ...

Guillain-Barre Syndrome, an acute flaccid paralysis known to be caused by recent Gastro-intestinal infections mainly campylobacter, and Respiratory infections mainly mycoplasma pneumoniae and influenza. One reported case of severe invasive pneumococcal disease in a 68 year old female, that presented with Austrian's triad of meningitis, pneumonia and endocarditis, and progressed to develop Guill...

INTRODUCTION Differing patterns of neurophysiological abnormalities have been reported in patients with Fisher syndrome. Fisher syndrome is rare, and few series have incorporated prospective serial studies to define the natural history of nerve conduction studies in Guillain-Barré syndrome. METHODS In an ongoing prospective study of Guillain-Barré syndrome patients, patients who presented wit...

INTRODUCTION Acute Human Immunodeficiency Virus infection is associated with a range of neurological conditions. Guillain-Barré syndrome is a rare presentation; acute inflammatory demyelinating polyneuropathy is the commonest form of Guillain-Barré syndrome. Acute inflammatory demyelinating polyneuropathy has occasionally been reported in acute Immunodeficiency Virus infection but little data e...