In this study elements of validation of headspace GC method of determination of residual methanol, n-pentane, ethanol, tert-butylamine, 2propanol, acetonitrile, dichloromethane and toluene in pharmaceutical substance are presented. Validation of the method included: selectivity, system precision, method precision, accuracy (recovery), limits of detection and quantitation (in substance), robustn...

INTRODUCTION The STOP TB Partnership aims to improve global tuberculosis (TB) control through expanding access to the directly observed treatment short course (DOTS) strategy. One approach to this is 'Engaging all Care Providers', which evolved from 'Public-Private Mix (PPM) DOTS'. The overall aim of this study was to systematically assess whether and to what degree the STOP TB Partnership's fo...

INTRODUCTION Inhaled nitric oxide (iNO) improves outcomes when given post systemic ischemia/reperfusion injury. iNO given during cardiopulmonary resuscitation (CPR) may therefore improve return of spontaneous circulation (ROSC) rates and functional outcome after cardiac arrest (CA). METHODS Thirty male Sprague-Dawley rats were subjected to 10 minutes of CA and at least 3 minutes of CPR. Anima...

An experiment of 10 weeks duration was conducted on 48 weaned female rats (285.2 ± 1.95 g) of strain Sprague Dawley to study the effect of replacing dietary Zn (12 ppm) supplementation from inorganic (ZnCO3) to organic (Zn nicotinate; Zn-nic) source at lower (6 or 9 ppm) or equal (12 ppm) levels on Zn retention and ovarian follicular population. Higher Zn concentration (on day 42) in serum (P<0...

This paper throws light on household cooking related exposures and level of indoor air pollutants (particulate matter and gaseous pollutants CO, CO2, SO2, NO, NO2) in different exposure area from the different types of cooking fuels used. Still the prevalence of biomass fuels exists in Indian households, combustion of which releases higher levels of solid and gaseous pollutants during the cooki...

Effects of chemical fertilizers (urea, super phosphate and potash) on toxicities of two carbamate insecticides, carbaryl and carbofuran, individually to the N2-fixing cyanobacterium, Cylindrospermum sp. were studied in vitro at partially lethal levels (below highest permissive concentrations) of each insecticide. The average number of vegetative cells between two polar heterocysts was 16.3 in c...

This study aims to characterize salmonid manures and to determine their potential use in agricultural soils. Sampling was carried out below salmon and trout cages in farms located in lakes and in the sea in the South of Chile during 2002-2003. Manure was analyzed for macronutrients, micronutrients and heavy metals. Results showed a high variability between samples and differences between sea an...

BACKGROUND Prosthesis-patient mismatch (PPM) may affect the clinical outcomes of patients undergoing aortic valve replacement (AVR). We aimed to determine the incidence of PPM, its effect on short-term mortality, and the factors contributing to PPM in China. METHODS We retrospectively examined all consecutive patients with isolated or concomitant AVR at our hospital between January 1, 2013 an...

We present a method for calculating accurate random coil chemical shift values of proteins. These values are obtained by analyzing the relationship between the amino acid sequences in flexible loop regions of native states and the corresponding experimentally measured chemical shifts. We estimate the errors in the random coil chemical shift scales to be 0.31 ppm for (13)C(alpha), 0.37 ppm for (...

6-Phenylethyl alcohol and 6-phenylethyl acetate have rose-like flavors and are yery important aroma components of higher boiling points in various alcoholic beverages, 6Phenylethyl alcohol exists in fairly large quantity in various alcoholic beverages, e.g., 40-60 ppm in sake, 1O-I5 ppm in whisky, 15-20 ppm in beer, 5-6 ppm in brandy, and 30-40 ppm in shouchu,i) We expected that the increase of