Experience-dependent plastic changes in the central sensory systems are due to activation of both the sensory and neuromodulatory systems. Nonspecific changes of cortical auditory neurons elicited by pseudo-conditioning are quite different from tone-specific changes of the neurons elicited by auditory fear conditioning. Therefore, the neural circuit evoking the nonspecific changes must also be ...

BACKGROUND Chronic spontaneous urticaria (CSU) is associated with considerable burden, but data from European patients are limited. METHODS This study is a retrospective, cross-sectional analysis of National Health and Wellness Survey data from the five largest EU countries (5EU: France, Germany, Italy, Spain, and the UK) collected between 2010 and 2013. Burden of disease for patients with CS...

5 This paper describes the transformation of the CSU-CHILL National Radar Facility from 6 a single-frequency (S-band) dual-polarization Doppler weather radar system to a dual7 frequency (S and X band) dual-polarization Doppler system with coaxial beams. A brief 8 history regarding the development of dual-wavelength radars is first presented. In the past 9 dual-wavelength measurements were used ...

Introduction Oxidative stress is a result of an imbalance between endogenous production of free reactive oxygen species and reduced effectiveness of antioxidant defence mechanisms. Advanced glycation end products (AGEs) and advanced oxidation protein products (AOPPs) are compounds formed by transformation of macromolecules, including proteins which can serve as markers of oxidative stress and i...

BACKGROUND Chronic spontaneous urticaria (CSU) is a common skin disorder with etiology that is not well understood. METHODS In this study, we evaluated the prevalence of autologous serum skin test (ASST) and skin prick testing (SPT) to house dust mite (HDM) in 862 CSU cases in China. Clinical features, courses and treatment responses were also recorded. RESULTS The prevalence of positive AS...

Introduction Urticaria and angioedema lasting more than 6 weeks have been designated as chronic urticaria (CU). It encompasses two major subtypes: chronic spontaneous urticaria (CSU) (previously known as chronic idiopathic urticaria) (CIU) and chronic inducible urticaria. CSU has been defined as wheals and/or angioedema that are endogenous and independent of any external physical stimulus. It a...

Summary Background. Histamine release (HR) test has previously been shown to predict the presence of endogenous histamine-releasing factors in chronic spontaneous urticaria (CSU). Objectives and methods. Twenty CSU patients unresponsive to antihistamine treatment were enrolled in order to evaluate the correlations between HR test results and demographic features, quality of life, disease activi...

BACKGROUND There is a felt need for trying newer therapeutic modalities in patients with chronic spontaneous urticaria, especially in the subset of patients classified as non-responders to antihistamines. Autologous serum therapy is an upcoming modality of treatment, and we decided to study its efficacy by subcutaneous route. AIMS To evaluate the effectiveness of subcutaneous autologous serum...