The correlations between intramyocellular lipid (IMCL), decreased fatty acid oxidation (FAO), and insulin resistance have led to the hypothesis that impaired FAO causes accumulation of lipotoxic intermediates that inhibit muscle insulin signaling. Using a skeletal muscle-specific carnitine palmitoyltransferase-1 KO model, we show that prolonged and severe mitochondrial FAO inhibition results in...

During activation, T cells undergo metabolic reprogramming, which imprints distinct functional fates. We determined that on PD-1 ligation, activated T cells are unable to engage in glycolysis or amino acid metabolism but have an increased rate of fatty acid β-oxidation (FAO). PD-1 promotes FAO of endogenous lipids by increasing expression of CPT1A, and inducing lipolysis as indicated by elevati...

Enabling environments for agribusiness and agro-industries development Regional and country perspectives The designations employed and the presentation of material in this information product do not imply the expression of any opinion whatsoever on the part of the Food and Agriculture Organization of the United Nations (FAO) concerning the legal or development status of any country, territory, ...

The pyfao56 software package is a Python-based implementation of (1) the American Society Civil Engineers (ASCE) Standardized Reference Evapotranspiration Equation and (2) Food Agricultural Organization United Nations (FAO) Irrigation Drainage Paper No. 56 (FAO-56) dual crop coefficient methodology. was initially developed to support water use estimation irrigation scheduling for field research...

The designations employed and the presentation of material in this information product do not imply the expression of any opinion whatsoever on the part of the Food and Agriculture Organization of the United Nations (FAO) or of the World Health Organization (WHO) concerning the legal or development status of any country, territory, city or area or of its authorities, or concerning the delimitat...

Traditionally, potatoes are a central component of warm meals in many European countries (Wandel et al. 2001; FAO, 2004). In an analysis from the EPIC study (n 13 031 men and 22 924 women) including data from ten European countries (Greece, Spain, Italy, France, Germany, The Netherlands, UK, Denmark, Sweden and Norway), potatoes contributed on average 7 % to the total carbohydrates consumed, bu...

An interdepartmental programme for Improving support for enhancing livelihoods of the rural poor. Cover photograph from FAO Photo-library This paper was prepared under contract with the Food and Agriculture Organization of the United Nations (FAO). The positions and opinions presented are those of the author alone, and are not intended to represent the views of FAO. The Livelihood Support Progr...

The designations employed and the presentation of material in this information product do not imply the expression of any opinion whatsoever on the part of the Food and Agriculture Organization of the United Nations (FAO) or of the World Health Organization (WHO) concerning the legal or development status of any country, territory, city or area or of its authorities, or concerning the delimitat...

Historically, the oceans were considered limitless and thought to harbour enough fish to feed an ever-increasing human population. However, the demands of a growing population, particularly in poorer countries, now far outstrip the sustainable yield of the seas. At the same time as fishing has become more industrialised, and wild fish stocks increasingly depleted, aquaculture production—fish an...