This study aimed to investigate the expression of N-methyl-D-aspartate receptor 1 (NMDAR1) and neuronal constitutive nitric oxide synthase (ncNOS) during form-deprivation myopia (FDM). FDM models were established in guinea pigs with facemasks. NMDAR1 expression in the retina was detected by immunohistochemistry and Western blot analysis. ncNOS mRNA expression was examined by in situ hybridizati...

PURPOSE To investigate whether the Sonic hedgehog (Shh) signaling induces myopic development by increasing the expression of matrix metalloproteinase (MMP)-2 in guinea pigs. METHODS A translucent diffuser was glued onto the right eye to induce form-deprivation myopia (FDM) in 10 guinea pigs. Four guinea pigs were served as a control group. The other 100 guinea pigs were subdivided into 5 grou...

PURPOSE Fibroblast growth factor-2 (FGF2) has been implied in the development of myopia according to previous studies investigating FGF2 in the sclera and retinal pigment epithelium. This study measured retinal FGF2 gene expression in an animal model and also tested for the association between single nucleotide polymorphisms (SNPs) in FGF2 and high myopia. METHODS The guinea pigs were assigne...

Fused Deposition Modeling (FDM) is a kind of Rapid prototyping (RP) technique, which allows direct transformation of CAD files into physical models. This paper attempts to identify and study the influence of electroplating layer thickness on the mechanical strength of Acrylonitrile butadiene styrene (ABS) samples developed from the FDM process. The study is conducted on the tensile test samples...

Fused deposition modeling (FDM) is one of the rapid prototyping technologies that can use plastic material, which can be effectively used for making patterns for investment casting. The surface finish of the investment casting depends upon the surface finish of the pattern. But the surface finish of the parts produced by using FDM is not very good as compared to wax patterns, which are conventi...

Diffuse optical tomography (DOT) has been studied for use in the detection of breast cancer, cerebral oxygenation, and cognitive brain signals. As optical imaging studies have increased significantly, acquiring imaging data in real time has become increasingly important. We have developed frequency-division multiplexing (FDM) DOT systems to analyze their performance with respect to acquisition ...

1. Introduction and historical remarks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160 2. Spectral estimators, parameter estimators and nonlinear problems . . . . . . . . . . . . . . . . . . . . . . . . . . . 164 3. Non-Hermitian quantum mechanics: connection to the harmonic inversion problem (HIP) . . . . . . . . . 167 4. HIP can be solve...