A cDNA clone (glx-2c) encoding glyoxal oxidase (GLOX) was isolated from a Phanerochaete chrysosporium lambda gt11 library, and its nucleotide sequence was shown to be distinct from that of the previously described clone glx-1c (P. J. Kersten and D. Cullen, Proc. Natl. Acad. Sci. USA 90:7411-7413, 1993). Genomic clones corresponding to both cDNAs were also isolated and sequenced. overall nucleot...

A concise total synthesis of mesembrine (four steps from known compound) was achieved both racemically and asymmetrically. Two key reactions were used here. One is the Rh(I)-catalyzed [5 + 1] cycloaddition of vinylcyclopropane 3c and CO. The other one is Buchwald's Pd-catalyzed coupling reaction that coupled β,γ-cyclohexenone 2c with aryl bromide 5 (using dppe ligand for racemic or (S)-Antphos ...

Coffee processing is a major contributor to the creation of food and product waste. Using coffee co-products can play an essential role in addressing environmental problems issues with nutritionally unbalanced foods, population growth, food-related diseases. This research aimed determine quality sensory parameters (aw, pH, dry matter, TAC, TPC, fat, fatty acids profile, fiber, caffeine, chlorog...

a. We recommend referral to a specialist renal service or nephrologist in the following situations: i. Stage 4 and 5 chronic kidney disease of any cause (estimated glomerular filtration rate <30mL/min/1.73m 2 ) (1C) ii. Persistent significant albuminuria (albumin creatinine ratio ≥30 mg/mmol, approximately equivalent to protein creatinine ratio ≥50 mg/mmol, or urinary protein excretion ≥500 mg/...

BACKGROUND Postoperative coronal imbalance is a significant problem after selective thoracic fusion for primary thoracic and compensatory lumbar curves in adolescent idiopathic scoliosis (AIS). However, longitudinal studies on postoperative behavior of coronal balance are lacking. This multicenter retrospective study was conducted to analyze factors related to onset and remodeling of postoperat...

The products of three human homeobox containing (HOX) genes, 2C, 3C and 4B, were produced in insect cells using the Baculovirus expression system and purified to near homogeneity. In this system we observed that the DNA binding forms of the three proteins are not glycosylated. HOX 3C and 4B are phosphorylated in insect cells, while HOX 2C is not. The three HOX proteins bind to a DNA sequence kn...

إ ةيرهجملا جماربلا لمشي اذهو ،ةيرورملا ةآرحلا ةاآاحم جمارب روطت يف مهاس ةيتامولعملا ايجولونكتلا يف ريبكلا مدقتلا ن ) Microscopic ( ، نلا ىلع بلطلا ةاآاحم اًضيأ لمشي نايحلأا ضعب يفو ، تاعطاقتو قرط نم اهيف امب لقنلا ةموظنم ةاآاحمب حمسيل يللآا بساحلا تاقيبطت قاطنو لق . ةيرهجملا ةيرورملا ةآرحلا ةاآاحم جمارب نيب نراقتو عجارت ةقرولا هذهو ) Microscopic ( ةيلومشلاو ) Macroscopic ( فلاتخلاا هجوأ ىلع ةزآر...

عوامل متعددی بر روند تاثیرگذاری نگاره های ایران شبه قاره هند در دوران حکومت مغولان موثر بوده است. موضوع این پژوهش بررسی نگارگری دوره با منابع کتابخانه ای و بکارگیری روش توصيفی- تحليلی رویکرد تاریخی، آثار از منظر شیوه پیدایش، ساختار، خصایص صوری تاثیرپذیری هنر ایرانی مورد قرار گرفته ‏است. اساس نتایج پژوهش، عصر مغولان، به گونه چشم گیر معرف نفوذ طور کلی، گرایش هنرمندان مغول هنرهای تصویری ایران‏ قوا...

In the past few years, Convolutional Neural Networks (CNN) have demonstrated promising performance in various real-world cybersecurity applications, such as network and multimedia security. However, underlying fragility of CNN structures poses major security problems, making them inappropriate for use security-oriented including computer networks. Protecting these architectures from adversarial...

In the present study some substituted benzimidazole derivatives were screened for several biological activities. The synthesized compounds subjected to evaluation of central analgesic, anti-inflammatory, cytotoxicity, antimicrobial and antioxidant activities by radiant heat induced tail flicking, carrageenan rat paw edema inhibition, brine shrimp lethality bioassay, disc diffusion DPPH free rad...