نتایج جستجو برای: دودمان سلولی nih3t3

تعداد نتایج: 13225  

Journal: :World Chinese Journal of Digestology 2010

Journal: :international journal of endocrinology and metabolism 0
hossein piri department of biochemistry and nutrition, school of medicine, hamadan university of medical science, ir iran bahram kazemi cellular and molecular biology research center, shahid beheshti university of medical science, ir iran; biotechnology department, faculty of medicine, shahid beheshti university of medical science, ir iran mohsen rezaei department of biochemistry and nutrition, school of medicine, hamadan university of medical science, ir iran mojgan bandehpour cellular and molecular biology research center, shahid beheshti university of medical science, ir iran; biotechnology department, faculty of medicine, shahid beheshti university of medical science, ir iran iraj khodadadi department of biochemistry and nutrition, school of medicine, hamadan university of medical science, ir iran taghi hassanzadeh department of biochemistry and nutrition, school of medicine, hamadan university of medical science, ir iran

background type 1 diabetes mellitus is one of the metabolic diseases that cause insulin-producing pancreatic ß cells be destroyed by immune system self-reactive t cells. recent­ly, new treatment methods have been developed including use of the stem cells, ß islet cells transplantation and gene therapy by viral and non-viral gene constructs. objectives the aim of this project was preparing the n...

پایان نامه :دانشگاه رازی - کرمانشاه - پژوهشکده علوم 1388

از دست رفتن کاردیومیوسیت ها بر اثر حمله ی قلبی منجر به نقائص غیرقابل بازگشت در عملکرد قلبی می گردد. پیوند سلول بنیادین بعد از سکته ی قلبی جهت بازیابی عملکرد قلب مورد بررسی قرار گرفته است. سلول های بنیادین مزانشیمی، دارای دو ویژگی منحصر به فرد می باشند: توانایی خود بازسازی برای مدت طولانی و پتانسیل بالای تمایزی. سلول های بنیادین مزانشیمی مغز استخوان انسان می توانند تحت شرایط القایی مناسب به دودم...

Journal: :Molecular medicine 1995
R Wong X G Zhu M A Pineda S Y Cheng B D Weintraub

BACKGROUND Mutations in the ligand-binding domain of the thyroid hormone receptor beta (TR beta) gene cause the syndrome of resistance to thyroid hormone (RTH). The clinical phenotype results from the antagonism of the normal TR alpha and the non-mutated TR beta alleles by the TR beta 1 mutants, via a dominant negative effect. There is, however, marked heterogeneity of organ resistance within a...

Journal: :The Journal of biological chemistry 2002
Roman Köhl Marianne Antoine Kerstin Reimers Paul Kiefer

NIH3T3 cells transformed by mouse FGF3-cDNA (DMI cells) selected for their ability to grow as anchorage-independent colonies in soft agar and in defined medium lacking growth factors exhibit a highly transformed phenotype. We have used dominant negative (DN) fibroblast growth factor (FGF) receptor 2 (FGFR2) isoforms to block the FGF response in DMI cells. When the DN-FGFR was expressed in DMI c...

2012
Karolina Błajecka Marin Marinov Laura Leitner Kristin Uth Guido Posern Alexandre Arcaro

The regulation of cell morphology is a dynamic process under the control of multiple protein complexes acting in a coordinated manner. Phosphoinositide 3-kinases (PI3K) and their lipid products are widely involved in cytoskeletal regulation by interacting with proteins regulating RhoGTPases. Class II PI3K isoforms have been implicated in the regulation of the actin cytoskeleton, although their ...

ژورنال: دانشور پزشکی 2011
بیرامی جمال, فیروزه , تهرانیان, نجمه , حاجی‌زاده, ابراهیم , حسین‌نژاد, آرش , دلفی, لادن , سپهری, حوری , صراف‌نژاد, عبدالفتاح , مهدی‌پور, پروین ,

Background and Objective: This study was conducted to evaluate the effect of PectaSol on modification of Doxorubicin (Dox) cytotoxicity and apoptosis and cell cycle in prostate cancer cell lines (DU-145 & LNCaP)                                                         Materials and Methods: Human prostate carcinoma DU-145 and LNCaP cell lines were treated with various concentrations of pectaSol,...

Journal: :The Journal of biological chemistry 2008
Yi-Chun Kuo Kai-Yun Huang Chung-Hsiang Yang Yu-San Yang Wen-Yu Lee Chi-Wu Chiang

Akt is a protein serine/threonine kinase that is involved in the regulation of diverse cellular processes. Phosphorylation of Akt at regulatory residues Thr-308 and Ser-473 leads to its full activation. The protein phosphatase 2A (PP2A) has long been known to negatively regulate Akt activity. The PP2A holoenzyme consists of the structural subunit (A), catalytic subunit (C), and a variable regul...

مواد پکتینی، پلی ساکارید های پیچیده غنی از زیر واحد های گالاکتوز می باشند. مطالعات نشان داده است که، این مواد قادر به القای آپوپتوز در سلولهای سرطانی هستند. تحقیق حاضر جهت بررسی اثر آپوپتوزی اسید پکتیک (AP) و پکتین مرکبات (CP) روی دودمان سلولی سرطان پروستات انسانی DU145  ، که وابسته به آندروژن می باشد، صورت گرفته است. با تغییر pH و دما نمونه های تغییر یافته ای از اسید پکتیک و پکتین مرکبات به دس...

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