In 60 human tissue samples (encompassing skeletal muscle, heart and kidney) obtained from subjects aged from under 1 to 90 years, we used quantitative PCR procedures to quantify mitochondrial DNA (mtDNA) molecules carrying the 4977 bp deletion (mtDNA4977) and 3243 A-->G base substitution. In addition, the prevalence of multiple mtDNA deletions was assessed in a semi-quantitative manner. For all...

Evaluation of antimicrobial potential and cytotoxic of Pouteria venosa species Raíssa Fernanda Evangelista Pires dos Santos, Isabelle Souza de Mélo Silva Silva , Eleci Adriano Hendges, Andressa Letícia Lopes da Silva, Andriele Mendonça Barbosa, Klebson Silva Santos, Renata Rego de Souza, Thais Honório Lins, Regina Célia Santos Sales Verissimo, Francine Ferreira Padilha, Eliane Aparecida Campesa...

The composition, environmental fate, and effects of the polybrominated biphenyls (Firemaster BP-6 or FF-1) involved in the accidental contamination of cattle feed in Michigan in 1973 are reviewed. Toxic effects referred to in this report are limited to those occurring in domestic and laboratory animals and include general toxicity, neurobehavioral toxicity, immunotoxicity, reproductive toxicity...

An accurate tool for viral typing is important for management of patients with human papillomavirus (HPV) infection and to monitor HPV vaccine efficacy. This study evaluated the performance of the HPV sign® Genotyping Test by analyzing 87 archival cervical specimens and compared results with historical data by INNO-LiPA HPV Genotyping Extra assay. There was a substantial concordance for HPV det...