Background:
 Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). Pathogenic T cells, such as Th1 and Th17, infiltrate CNS, resulting in neuroinflammation, demyelination axonal damage. activates microglia (MG) CNS Th17 acts a chemokine to recruit immune cells into CNS. MG resident cell its activation associated with destruction myelin secretion inflammatory...