It has been well documented that protein kinase C (PKC) plays an important role in regulation of phospholipase D (PLD) activity. Although PKC regulation of PLD1 activity has been studied extensively, the role of PKC in PLD2 regulation remains to be established. In the present study it was demonstrated that phorbol 12-myristate 13-acetate (PMA) induced PLD2 activation in COS-7 cells. PLD2 was al...

The hepatitis A virus (HAV), which can be a threat to humans, found in oysters. Oysters need sterilization technology that does not cause quality changes because they are eaten raw. Therefore, this study, antiviral effects and were conducted using dielectric barrier discharge plasma (DBDP). Total titers of non-PMA- PMA-treated suspensions HAV reduced 0.20–1.05 0.35–1.49 log10 copies/μL, respect...

Herein, a mechanism is proposed as to how thin films formed from Heusler compound can simultaneously have both perpendicular magnetic anisotropy (PMA) and be half‐metallic. It that film half‐metallic full‐Heusler or half‐Heusler cubic in the bulk undergo tetragonal distortion by adopting lattice constant of underlayer material during deposition process. The value this tuned using materials with...

It has been well documented that protein kinase C (PKC) plays an important role in regulation of phospholipase D (PLD) activity. Although PKC regulation of PLD1 activity has been studied extensively, the role of PKC in PLD2 regulation remains to be established. In the present study it was demonstrated that phorbol 12myristate 13-acetate (PMA) induced PLD2 activation in COS-7 cells. PLD2 was als...

Sphingolipid metabolism was examined in guinea-pig airway smooth muscle cells stimulated by platelet-derived growth factor (PDGF) and 4β-phorbol 12- myristate 13-acetate (PMA), as mitogens and bradykinin (BK) as non-mitogen. Stimulation of the cells by PMA and PDGF for 60 min. at 37°C induced the following changes in sphingolipid metabolites: in cells prelabeled with PH] palmitate, a 1.2 f...

Previously, we reported that phorbol 12-myristate 13-acetate (PMA)-activated protein kinase C (PKC) induced Rac1 activation in A172 glioblastoma cells. In this study, we investigated the mechanism of PMA-activated PKC-induced migration of glioblastoma cells by focusing on Rac1. PMA-induced formation of lamellipodia and focal complexes following migration were blocked by inhibiting Rac1 with sma...