Herpes simplex virus 1 (HSV-1) Us3 protein kinase phosphorylates threonine at position 887 (Thr-887) in the cytoplasmic tail of envelope glycoprotein B (gB) in infected cells. This phosphorylation downregulates cell surface expression of gB and plays a role in viral pathogenesis in the mouse herpes stromal keratitis model. In the present study, we demonstrated that Us3 phosphorylation of gB Thr...

16 guitar intro w/ rhythm and lead guitars Bm /Gb /D#m /Gb(nonbar chords) Verse 1 Bm Gb I believe you're the One, I believe ya' D#m Gb Your hand was there to save me when my ship was goin' down Bm Gb You were there to dust me off and recieve me D#m Gb I'm not the same I bless your Name, I'm so glad that I'm found Bm Gb I hear your Word; I feel your love Lord, I need ya D#m Gb No man or no woman...

BACKGROUND Infection with multiple CMV strains is common in immunocompromised hosts, but its occurrence in normal hosts has not been well-studied. METHODS We analyzed CMV strains longitudinally in women who acquired CMV while enrolled in a CMV glycoprotein B (gB) vaccine trial. Sequencing of four variable genes was performed in samples collected from seroconversion and up to 34 months thereaf...

introduction: glycoprotein b (gb) is the major antigen for induction of humoral responses against human cytomegalovirus (hcmv) making it an attractive candidate for immune prophylaxis. in the present study, the humoral immune response of balb/c mice to a truncated hcmv gb protein fused with gfp was evaluated. methods: the truncated gb coding sequence was synthesized and cloned in pegfpn1 eukary...

Functional dyspepsia (FD) is a constellation of epigastric symptoms originating in the gastroduodenal region without organic and metabolic cause. However, similar confounding symptoms can also appear in patients with gallbladder (GB) dyskinesia. Therefore, symptoms of GB dyskinesia may be mistaken for FD. We aimed to identify GB dyskinesia as a cause of FD symptoms compatible with the Rome IV c...

Glycoproteins homologous to the type I membrane glycoprotein B (gB) of herpes simplex virus 1 (HSV-1) are the most highly conserved glycoproteins within the family Herpesviridae and are present in members of each herpesvirus subfamily. In the alphaherpesvirus pseudorabies virus (PrV), gB is required for entry into target cells and for direct viral cell-to-cell spread. These processes, though re...

Pot marigold (Calendula officinalis L.) is widely used due to its various biological activities to treat diseases as an analgesic, anti-diabetic, anti-ulcer and anti-inflammatory agent. To ameliorate the adverse effects of water stress on this medicinal plant, foliar application of glycine betaine (GB) and L-arginine (LA) was ...