OBJECTIVE Diabetes, hypertension, infections, and nephrotoxicity of certain immunosuppressive drugs (i.e., calcineurin inhibitors) can reduce functional survival of the kidney graft. Our aim was to evaluate survival, hypertrophy, and vascular function of the kidney graft in end-stage renal disease (ESRD) type 1 diabetic patients after transplant. RESEARCH DESIGN AND METHODS The study populati...

β-cells in the pancreatic islet respond to elevated plasma glucose by secreting insulin to maintain glucose homeostasis. In addition to glucose stimulation, insulin secretion is modulated by numerous G-protein coupled receptors (GPCRs). The GPCR ligands Kisspeptin-10 (KP) and glucagon-like peptide-1 (GLP-1) potentiate insulin secretion through Gq and Gs-coupled receptors, respectively. Despite ...

Klebsiella pneumoniae (KP) is the most common pathogen of pyogenic liver abscess in East and Southeast Asia and diabetes mellitus (DM) is a major risk factor. The effect and mechanism of diabetes on KP liver abscess was examined in streptozotocin-induced diabetic mice and Akita mice (C57BL/6J-Ins2Akita). KP translocation to liver and plasma alaine transaminase levels were increased and liver cl...

We investigate the Miura map between the dispersionless KP and dispersionless modified KP hierarchies. We show that the Miura map is canonical with respect to their bi-Hamiltonian structures. Moreover, inspired by the works of Takasaki and Takebe, the twistor construction of solution structure for the dispersionless modified KP hierarchy is given.

We propose a hamiltonian formulation of the N = 2 supersym-metric KP type hierarchy recently studied by Krivonos and Sorin. We obtain a quadratic hamiltonian structure which allows for several reductions of the KP type hierarchy. In particular, the third family of N = 2 KdV hierarchies is recovered. We also give an easy constrution of Wronskian solutions of the KP and KdV type equations.

The genus-1 Kadomtsev-Petviashvili (KP)-Whitham system is derived for both variants of the KP equation; namely the KPI and KPII equations. The basic properties of the KP-Whitham system, including symmetries, exact reductions and its possible complete integrability, together with the appropriate generalization of the one-dimensional Riemann problem for the Korteweg-de Vries equation are discusse...

It is by now well known that the wave functions of rational solutions to the KP hierarchy which can be achieved as limits of the pure nsoliton solutions satisfy an eigenvalue equation for ordinary differential operators in the spectral parameter. This property is known as “bispectrality” and has proved to be both interesting and useful. In a recent preprint (mathph/9806001) evidence was present...

BACKGROUND In many Asian countries, Klebsiella pneumoniae (KP) is the second pathogen responsible for community-acquired pneumonia. Yet, very little is known about KP etiology in ALRI in Cambodia, a country that has one of the weakest medical infrastructures in the region. We present here the first clinico-radiological description of KP community-acquired ALRI in hospitalized Cambodian patients...

Candida albicans is a commensal organism, commonly inhabiting mucosal surfaces of healthy individuals, as a part of the resident microbiota. However, in susceptible hosts, especially hospitalized and/or immunocompromised patients, it may cause a wide range of infections. The presence of abiotic substrates, such as central venous or urinary catheters, provides an additional niche for Candida att...

The Dartmouth Atlas method for examination of variation in care at the end of life was replicated by Kaiser Permanente (KP). Variation within KP was analyzed and compared with corresponding Dartmouth Atlas Hospital Referral Regions. Although KP inpatient care use rates were 25% to 30% lower and hospice use rates were higher than in the surrounding communities, there was still two- to four-fold ...