نتایج جستجو برای: ایزوپروستان f2a
تعداد نتایج: 239 فیلتر نتایج به سال:
BACKGROUND/AIMS The authors investigated the concentrations of 8-isoprostaglandin F(2a), a marker of oxidative stress in vivo, and ascorbic acid, a protectant against oxidative damage, in the aqueous humour of patients with exfoliation syndrome (XFS) and cataract and compared the results with those in age matched patients with cataract, but without XFS, to determine whether XFS is associated wi...
Prostaglandins have been implicated in several neovascular diseases. In the present study, we found elevated FP receptor and vascular endothelial growth factor (VEGF) expression colocalized in glandular epithelial and vascular cells lining the blood vessels in endometrial adenocarcinomas. We investigated the signaling pathways activated by the FP receptor and their role in modulating VEGF expre...
Aims: The role of endothelium-derived contracting factors (EDCFs) in regulating renovascular function is yet to be elucidated in renovascular hypertension (RH). The current study investigated whether oxidative stressdependent cyclooxygenase (COX)-2-derived prostaglandin F2a (PGF2a) impairs endothelial function in renal arteries of renovascular hypertensive rats (RHR). Results: Renal hypertensio...
Eco-Ethology Research Unit, ISPA-Instituto Universitário, Rua Jardim do Tabaco 34, Lisboa 1149-041, Portugal Centro de Ciências do Mar, Universidade do Algarve, Campus de Gambelas, Faro 8005-139, Portugal Department of Science and Environment, University of St Joseph, Rua de Londres 16, Macau, People’s Republic of China (SAR) Champalimaud Neuroscience Programme, Instituto Gulbenkian de Ciência,...
A kidney epithelial cell line, LLC-PK1, which does not synthesize prostaglandins, provides an ideal in vitro model system to investigate the effect of prostaglandins in the regulation of renal ammoniagenesis. Previous studies from our laboratory have demonstrated significant increases in glutamine-dependent ammonia and alanine production by rocked cultures of LLC-PK1 cells subjected to either a...
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