Figure 1 Electroanatomic activation map during RA stimulation (A) before and (B) after MAP ablation. Signals obtained at the ablation catheter located at the free lateral wall are shown. MAP anatomical disposition (yellow dots). Right bundle branch anatomical disposition (blue dots). M =mahaim accessory pathway potential; MAPd = distal ablation catheter recording; MAPp = proximal ablation cathe...

Amyloid-β (Aβ) deposition is one of the hallmarks of the amyloid hypothesis in Alzheimer's disease (AD). Mouse models using APP-transgene overexpression to generate amyloid plaques have shown to model only certain parts of the disease. The extent to which the data from mice can be transferred to man remains controversial. Several studies have shown convincing treatment results in reducing Aβ an...

We employed quasielastic and static light scattering to measure apparent values of the mean hydrodynamic radii (Rh)app, molecular weights (Mapp), and radii of gyration (Rg)app in solutions containing mixed micelles composed of bile salts (cholate and taurochenodeoxycholate, both cholanoyl derivatives) and the glycoacyl chain detergent, octyl glucoside, with egg yolk phosphatidylcholine (EYPC) a...

Mitochondrial dysfunction and synaptic damage are early pathological features of the Alzheimer's disease-affected brain. Memory impairment in Alzheimer's disease is a manifestation of brain pathologies such as accumulation of amyloid-β peptide and mitochondrial damage. The underlying pathogenic mechanisms and effective disease-modifying therapies for Alzheimer's disease remain elusive. Here, we...

Small and large macromolecular activators of phagocytosis from platelets (S-MAPP and L-MAPP, respectively) are released from activated platelets and enhance Fcγ receptor-mediated phagocytosis by neutrophils. Platelets stored in the form of platelet concentrates lose their MAPPproducing activity within 48 h, but recover it when incubated in dialyzed plasma against PBS and supplemented with Ca++....

Amaç: Hemodiyaliz (HD) hastalarında protein-enerji malnütrisyonu, kas kütlesi ve işlev kaybı sık görülmektedir. Bu çalışmanın amacı; HD malnütrisyon sarkopeni görülme sıklığını tespit etmektir. Bireyler Yöntem: Yaş ortalaması 50.9±13.8 yıl olan 40 hemodiyaliz hastası çalışmaya dahil edilmiştir. Hastalara R-MAPP (Uzaktan Malnütrisyon Uygulaması) taraması yapılmıştır. uygulama Evrensel Tarama Ara...