Hexosamines have been hypothesized to mediate aspects of glucose sensing and toxic effects of hyperglycemia. For example, insulin resistance results when the rate-limiting enzyme for hexosamine synthesis, glutamine:fructose-6-phosphate amidotransferase (GFA), is overexpressed in muscle and adipose tissue of transgenic mice. The glucose infusion rates required to maintain euglycemia at insulin i...

In the Fe-Co alloy system, addition of Cr improves glass-forming ability (GFA) with superior soft magnetic properties such as high saturation magnetization (Ms) and low coercivity (Hc). addition, is considered to be an important factor for improving corrosion resistance Fe-based amorphous alloy. Therefore, in present study, we investigated GFA, properties, as-spun ribbons [Co0.075Fe0.675B0.2Si0...

The R package GFA provides a full pipeline for factor analysis of multiple data sources that are represented as matrices with co-occurring samples. It allows learning dependencies between subsets of the data sources, decomposed into latent factors. The package also implements sparse priors for the factorization, providing interpretable biclusters of the multi-source data.

In the present study, effect of wet mechanical alloying (MA) on glass-forming ability (GFA) Co43Fe20X5.5B31.5 (X = Ta, W) alloys was studied. The structural evolution during MA investigated using high-energy X-ray diffraction, absorption spectroscopy, high-resolution transmission electron microscopy and magnetic measurements. Pair distribution function extended fine structure spectroscopy were ...

Yoctosecond Quantitative Structure–Activity Relationship (QSAR) and Quantitative Structure-Property Relationship (QSPR) under synchrotron radiations using Genetic Function Approximation (GFA) algorithm studies are suggested for the prediction of solubility of anti–cancer Nano drugs in aqueous solutions in yoctosecond [1-16]. Ab initio and density functional theories were used to calculate some ...

By using the concepts of the short-range order (SRO) and middle-range order (MRO) characterizing structures, an attempt has been made to describe the glass forming ability (GFA) of liquid alloys. This includes the effect of more than two kinds of SRO in the liquid caused by the addition of second and third elements to a metallic solvent. The minimum solute concentration is related to the atomic...

Recently, a series of quaternary Zr-based bulk metallic glasses (BMGs), i.e., Zr53Cu18.7Ni12Al16.3, Zr51.9Cu23.3Ni10.5Al14.3 and Zr50.7Cu28Ni9Al12.3, have been developed and their glass-forming ability (GFA) increases with Cu concentration. In this work, atomic structures of the three BMGs were rebuilt by reverse Monte Carlo simulations based on the reduced pair distribution functions measured ...

Diffusion weighted imaging (DWI) is widely used to study microstructural characteristics of the brain. Diffusion tensor imaging (DTI) and high-angular resolution imaging (HARDI) are frequently used in radiology and neuroscience research but can be limited in describing the signal behavior in composite nerve fiber structures. Here, we developed and assessed the benefit of a comprehensive diffusi...