In this study, we aimed to investigate whether there was an association between fetal nuchal translucency (NT) and the serum markers plasma protein-A (PAPP-A) free beta-human chorionic gonadotropin (β-hCG) measured by first-trimester screening test, as well birth weight hypertension. 454 pregnant women who had undergone test for Down syndrome were included in study. All measurements values of N...

OBJECTIVE To determine if combinations of maternal characteristics and measurements of parameters used in screening for aneuploidies at 11-13 weeks provide significant prediction of macrosomia. METHOD Maternal characteristics, fetal nuchal translucency (NT), free β-human chorionic gonadotrophin (β-hCG) and pregnancy-associated plasma protein-A (PAPP-A) were recorded at 11(+0)-13(+6) weeks in ...

Background: Premature Rupture of Membranes (PROM) is common in obstetrics and management such patients depends on whether the rupture has occurred or not. With membranes ruptured fetus deprived protection provided within amniotic cavity. Beta-Human chorionic gonadotrophin (β-HCG) a hormone present high concentration fluid as well blood urine mother studied possible predictor preterm labour mark...

OBJECTIVE To establish normative weight-adjusted models for the median levels of first trimester serum biomarkers for trisomy 21 screening in southern Thai women, and to compare these reference levels with Caucasian-specific and northern Thai models. METHODS A cross-sectional study was conducted in 1,150 normal singleton pregnancy women to determine serum pregnancy-associated plasma protein-A...

OBJECTIVE To examine the performance of screening for trisomies 21, 18 and 13 at 11-13 weeks' gestation using specific algorithms for these trisomies based on combinations of fetal nuchal translucency thickness (NT), fetal heart rate (FHR), ductus venosus pulsatility index for veins (DV PIV), and serum free β-human chorionic gonadotropin (β-hCG), pregnancy-associated plasma protein A (PAPP-A), ...

Preoperative pregnancy testing is common practice among anesthesiologists. Little is re-ported in anesthesia literature on causes other than pregnancy for elevated human chorionic go-nadotrophin (hCG) levels. Among these causes is hCG secretion by tumors. This is a report of a female with pancreatic cancer that presented for a Whipple procedure, who on routine pregnancy testing was found to hav...

INTRODUCTION This study examines the effectiveness of double-marker analysis for α-fetoprotein (AFP) and β-human chorionic gonadotropin (β-hCG) combined with measurement of nuchal fold thickness (NT) in the detection of Down's syndrome (DS) in Mainland Chinese subjects during second trimester prenatal screening. MATERIALS AND METHODS We examined pregnant women with a singleton pregnancy betwe...

Background: Mid-trimester maternal serum markers have been used for prenatal aneuploidy screening a long time. The aim of the study was to assess mid-term levels β-human chorionic gonadotropin and alpha-fetoproteins placenta-mediated adverse pregnancy outcomes (PMAPOs) in preterm term pregnancies.
 Material methods: A prospective cohort involving nulliparous women with singletons without o...