Recombinant Der f2 (rDer f2) has recently been developed as a promising allergen for the diagnosis and immunotherapy of house-dust mite allergy, and studies in immunology. The aim of the present study was to evaluate whether oral administration of rDer f2 could suppress an immediate allergic reaction in mice sensitized with mite allergen. We developed a murine allergic model that showed broncho...

We use the following rule of composition of automorphisms: if φ, ψ ∈ Aut(F2) and x ∈ F2 then φψ(x) = ψ(φ(x)). For x ∈ F2 denote by St(x) the stabilizer of x in Aut(F2). For a subset X of a group denote by 〈X〉 the subgroup generated by X. Denote [x, y] = x−1y−1xy, x = y−1xy. For g ∈ F2 denote by ĝ the automorphism induced by the conjugation by g: ĝ(x) = g−1xg, x ∈ F2. Let − : Aut(F2) → GL2(Z) be...

We give an example of a Cayley graph [Formula: see text] for the group which is not minimally almost convex (MAC). On other hand, standard does satisfy falsification by fellow traveler property (FFTP), strictly stronger. As result, any lying between FFTP and MAC (i.e., text]) dependent on generating set. This includes well-known properties convexity, were already known to depend set as well Poé...

Translation of influenza A virus PB1-F2 occurs in a second open reading frame (ORF) of the PB1 gene segment. PB1-F2 has been implicated in regulation of polymerase activity, immunopathology, susceptibility to secondary bacterial infection, and induction of apoptosis. Experimental evidence of PB1-F2 molecular function during infection has been collected primarily from human and avian viral isola...

PB1-F2 protein is a factor of virulence of influenza A viruses which increases the mortality and morbidity associated with infection. Most seasonal H1N1 Influenza A viruses express nowadays a truncated version of PB1-F2. Here we show that truncation of PB1-F2 modified supramolecular organization of the protein in a membrane-mimicking environment. In addition, full-length PB1-F2(1-90) and C-term...

Acoustic studies of several languages indicate that second-formant (F2) slopes in high vowels have opposing directions (independent of consonantal context): front [iː]-like vowels are produced with a rising F2 slope, whereas back [uː]-like vowels are produced with a falling F2 slope. The present study first reports acoustic measurements that confirm this pattern for the English variety of Stand...