OBJECTIVE To evaluate the hepatoprotective and immunotherapeutic effects of aqueous extract of turmeric rhizome in CCl4 intoxicated Swiss albino mice. METHODS First group of mice (n=5) received CCl4 treatment at a dose of 0.5 mL/kg bw (i.p.) for 7 days. Second group was fed orally the aqueous extract of turmeric at a dose of 50 mg/kg bw for 15 days. The third group was given both the turmeric...

We conducted a cross-sectional study to investigate the clinical factors associated with mortality in patients with dengue viral infection at a tertiary care center over a 3 year period. Six hundred ninety-nine patients with a clinical diagnosis of dengue fever (DF), dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) during the study period were included in the study. Data were coll...

BACKGROUND Type 2 diabetes is an endocrine disorder that affects a large percentage of patients. High blood glucose causes fatty deposits in the liver which is likely to increase in SGOT and SGPT activities. Significant increase in SGOT/SGPT and low HDL levels is observed in patients with diabetes. Serum fructosamine concentration reflects the degree of blood glucose control in diabetic patient...

INTRODUCTION:Vector borne viral infections endangers billions of people and World Health Organization (WHO) has estimated about 50 million cases of dengue infection every year worldwide.This disease caused by dengue ranges from a relatively minor febrile illness to a life threatening condition characterized by extensive capillary leak. AIM: The present study aimed to prevent the complications a...

Demam tifoid adalah penyakit sistemik akut yang disebabkan oleh bakteri Salmonella typhi. typhi terdapat di usus halus akan berkembang biak kemudian menghasilkan endotoksin, mana endotoksin dihasilkan merupakan kompleks lipopolisakarida dan dianggap berperan penting pada patogenesis demam tifoid. Apabila masuk ke dalam tubuh menyebabkan kondisi menjadi lemah, sehingga memudahkan menyerang jarin...

Abstract The effect of consistent exposure of the inhabitants in the Niger Delta region of Nigeria to crude oil may induce undesirable biochemical changes in the biota. Alterations in some hepatic function indices of male and female albino rats exposed to Bonny light crude oil (BLCO) by skin application were investigated. Sub lethal dose (500mg/kg body weight) of the BLCO was applied to shaved ...

Background: Little information is available on the trend in cardiovascular risk factors and hepatic enzymes in Iranian seafarers. The present study aimed to assess the pattern of obesity, hypertension, diabetes, elevated serum glutamic oxaloacetate transaminase (SGOT), and serum glutamate pyruvate transaminase (SGPT) in Iranian seafarers during 2010 to 2014. Methods: Data on cardiovascular r...

Serum transaminases were determined according to the method ofKarmen, Wrobleski, and LaDue (1955) (normal values for our laboratory: SGOT and SGPT up to 15 i.u./ litre), serum salicylate levels with Trinder's reagent, fibrinogen according to the method of Clauss (1957), fibrinogen degradation products (FDP) by the immunodiffusion technique (Ouchterlony), and Factor V according to the method of ...

The hepatoprotective activity of the ethanolic extract of the rhizomes of Costus speciosus (Koenig) Sm. was studied on carbon tetrachloride treated rats. The extract registered a significant fall in the levels of serum glutamyl oxalacetic acid transaminase (SGOT), serum glutamyl pyruvate transaminase (SGPT), alkaline phosphatase (ALKP), serum bilirubin (SBLN) and liver inflammation supported by...

S ir, I read the article “Mildly Elevated Transaminases: Excellent diagnostic c l u e f o r A n i c t e r i c L e p t o s p i r o s i s ” with interest.1 Leptospirosis can be diagnosed only by laboratory tests as clinical features are non specific. But the laboratory tests are complex and hence definite guidelines for diagnosis of human leptospirosis is necessary. I fully agree that microscopic...