نتایج جستجو برای: آزمون های gof
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BACKGROUND Genetic causes of exaggerated or reduced pain sensitivity in humans are well known. Recently, single nucleotide polymorphisms (SNPs) in the gene P2RX7, coding for the ATP-gated ion channel P2X7, have been described that cause gain-of-function (GOF) and loss-of-function (LOF), respectively of this channel. Importantly, P2RX7 SNPs have been associated with more or less severe pain scor...
Software design patterns are a means to specify common solutions to reoccurring design problems. Similarly, security design patterns provide a means to encapsulate common security solutions and mechanisms which are applicable at the design phase of the software development lifecycle. Security patterns have received considerable attention from the security community to introduce concepts such as...
Cognitive radio (CR) is a promising technology for improving usage of frequency band. Cognitive radio users (CUs) are allowed to use the bands without interference in operation of licensed users. Reliable sensing information about status of licensed band is a prerequirement for CR network. Cooperative spectrum sensing (CSS) is able to offer an improved sensing reliability compared to individual...
Air pollution exposure has been shown to be associated with an increased risk of specific cancers. This study investigated whether the number and incidence of the most common cancers in Saudi Arabia were associated with urban air pollution exposure, specifically NO2. Overall, high model goodness of fit (GOF) was observed in the Eastern, Riyadh and Makkah regions. The significant coefficients of...
ly, the derivation of the grasp kinematics is identical to thefixed contact case except that the grasp map and hand Jacobian dependon the instantaneous contact location, which in turn depends on ηi, thecontact coordinates for each finger. Thus, the contact kinematics havethe formJh(θ, xo, η)θ̇ = GT (η)V bpoη̇i = Ai(ηi)V bofi ,(5.40) where η = (η1, . . . , η...
Chronic Mucocutaneous Candidiasis (CMC) is the chronic, recurrent, noninvasive Candida infections of the skin, mucous membranes, and nails. A 26-month-old girl was admitted with the complaints of recurrent oral Candidiasis, diarrhea, and respiratory infections. Candida albicans grew in oral mucosa swab. CMV and EBV DNA titers were elevated. She had hypergammaglobulinemia; IgE level, percentages...
Mutations in the p53 tumor suppressor gene are the most frequent genetic alteration in cancer and are often associated with progression from benign to invasive stages with metastatic potential. Mutations inactivate tumor suppression by p53, and some endow the protein with novel gain of function (GOF) properties that actively promote tumor progression and metastasis. By comparative gene expressi...
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