BACKGROUND The Food and Drug Administration (FDA) issues drug safety communications (DSCs) to health care professionals, patients, and the public when safety issues emerge related to FDA-approved drug products. These safety messages are disseminated through social media to ensure broad uptake. OBJECTIVE The objective of this study was to assess the social media dissemination of 2 DSCs release...

Dysspondyloenchondromatosis (DSC) is a rare skeletal dysplasia characterized by enchondroma-like lesions and anisospondyly. The former leads to discrepancies in limb length, and the latter, to progressive kyphoscoliosis. Two recent cases have highlighted the genetic heterogeneity of DSC, one demonstrating the presence and, the other, the absence of a COL2A1 mutation. This may have important cli...

Dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) following bolus injection of gadolinium contrast agent (CA) is widely used for the estimation of brain perfusion parameters such as cerebral blood volume (CBV), cerebral blood flow (CBF), and mean transit time (MTT) for both clinical and research purposes. Although it is predicted that DSC-MRI will have superior performance at...

This paper examines the room-temperature microstructure and mechanical properties of dispersion-strengthened-cast magnesium (DSC-Mg) containing 30 vol.% of 0.33 mm yttria dispersoids. The dispersoids are reasonably well distributed in both cast and extruded materials and the extruded matrix grains size is about 0.88 mm, in agreement with existing models on grain pinning. The Young’s modulus mea...

This paper examines the potential of mobile phones to be used as front-end sensors for photogrammetric procedures and applications. For this purpose, two mobile phone cameras (Sony Ericsson K750i and Nokia N93) were calibrated over an indoor 3D testfield, using a self-calibrating bundle adjustment. Geometric accuracy tests were carried out in order to evaluate their metric performances and to c...

Prednisolone is a safe antiinflammatory agent for the treatment of inflammatory diseases. To improve the aqueous solubility of the drug and dissolution rate, the complexation of prednisolone with skimmed milk was studied. A physical mixture and solid dispersion of prednisolone with skimmed milk were prepared. The lyophilization method was used to prepare the solid dispersion. Detection of inclu...

Differential Scanning Calorimetry (DSC) is a thermal analysis technique that measures the energy absorbed or released by a sample as a function of temperature or time. DSC has wide application for analysis of solid state reactions and solid-liquid reactions in many different materials. In recent years, DSC has been applied to analyze materials and alloys processed through Severe Plastic Deforma...

Background Brain tumor is one of the most common tumors. A successful treatment might be achieved with an early identification. Pathological investigation as the gold standard method for tumor identification has some limitations. Noninvasive assessment of tumor specifications may be possible using perfusion-weighted magnetic resonance imaging (MRI). Cerebral blood volume (CBV) and cerebral bloo...

Differential Scanning Calorimetry (DSC) is a thermal analysis technique that measures the energy absorbed or released by a sample as a function of temperature or time. Analysis by DSC has wide applications for examining solid-state reactions and solid-liquid reactions in many different materials. Quantitative analyses of the kinetics of reactions may be assessed by reviewing the interrelation b...