نتایج جستجو برای: β carboline

تعداد نتایج: 177796  

Journal: :The Journal of pharmacology and experimental therapeutics 2015
Ana Cristina G Grodzki Bhaskar Poola Nagarekha Pasupuleti Michael H Nantz Pamela J Lein Fredric Gorin

Neuropathic pain is a maladaptive immune response to peripheral nerve injury that causes a chronic painful condition refractory to most analgesics. Nitric oxide (NO), which is produced by nitric oxide synthases (NOSs), has been implicated as a key factor in the pathogenesis of neuropathic pain. β-Carbolines are a large group of natural and synthetic indole alkaloids, some of which block activat...

Journal: :Organic letters 2009
Barnali Maiti Kaushik Chanda Chung-Ming Sun

A novel ionic liquid (IL) supported, green synthetic protocol has been developed toward the synthesis of oxo and thio hydantoin analogues tethered with tetrahydro-beta-carboline by the use of focused microwave irradiation. IL-bound tryptophan underwent a Pictet-Spengler reaction with various carbonyl compounds to generate the IL-immobilized tetrahydro-beta-carbolines in aqueous isopropanol medi...

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