Interactions of the presynaptic protein α-synuclein with membranes are involved in its physiological action as well as in the pathological misfolding and aggregation related to Parkinsons's disease. We studied the conformation and orientation of α-synuclein bound to model vesicular membranes using multiparametric response polarity-sensitive fluorescent probes together with CD and EPR measuremen...

Sensitivity of endothelin-1 (ET-1)-ion channel interactions has been proposed to exceed that of ET-1-phospholipase activation in vascular smooth muscle. We wanted to determine whether short-circuiting ion channels with staphylococcal α-toxin pores would shift the ET-1-force relation to the right as predicted from the above proposal. Medium size porcine coronary arteries (outer diameter 0.7-1.5 ...

1. January 12th – Motivation (Bhargav Bhatt) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2. January 26th – Huber rings (Rankeya Datta). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2.1. Notation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....

In this work first we study the properties of nearsemirings to introduce an α-radical. Then we observe the role of near-semirings in generalized linear sequential machines, and we test the minimality through the radical. Introduction Holcombe used the theory of near-rings to study linear sequential machines of Eilenberg [1, 4]. Though the picture of near-rings in linear sequential machines is a...

We fabricate α-terthiophene single-molecule junctions (SMJs) and characterize their conductive states by the simultaneous measurements of surface-enhanced Raman scattering (SERS) electronic conductance. The SMJ showed broad conductance distribution due to different portions multiple aromatic rings connected electrodes. SERS spectra obtained measurement vibrational energy C−C stretching mode dep...

let $r$ be a reversible ring which is $alpha$-compatible for an endomorphism $alpha$ of $r$ and $f(x)=a_0+a_1x+cdots+a_nx^n$ be a nonzero skew polynomial in $r[x;alpha]$. it is proved that if there exists a nonzero skew polynomial $g(x)=b_0+b_1x+cdots+b_mx^m$ in $r[x;alpha]$ such that $g(x)f(x)=c$ is a constant in $r$, then $b_0a_0=c$ and there exist nonzero elements $a$ and $r$ in $r$ such tha...

we observe some new characterizations of $n$-presented modules. using the concepts of $(n,0)$-injectivity and $(n,0)$-flatness of modules, we also present some characterizations of right $n$-coherent rings, right $n$-hereditary rings, and right $n$-regular rings.

in this paper, we introduce the concept of the   generalized aip-rings as a generalization of the generalized quasi-   baer rings   and generalized p.p.-rings. we show that the class of the generalized aip-rings is closed under direct products and morita invariance. we also characterize the 2-by-2 formal upper triangular matrix rings of this new class of rings. finally, we provide sever...

This paper gives a method to construct rigid spaces, which is similar to the method used to construct toric schemes.

In order to elucidate the role of desorption/ionization efficiency of peptides in MALDI-MS, we focused on peptides with disulfide bonds, which form a rigid tertiary structure. We synthesized seven sets of peptides with one disulfide bond (oxytocin, somatostatin, [Arg(8)]-vasopressin, [Arg(8)]-vasotocin, cortistatin, melanin-concentrating hormone, urotensin II-related peptide) and five sets of ...