A new synthetic approach towards the preparation of functionalised, soluble, donor-acceptor (DA) alkylbithiophene derivatives of oxadiazole, thiadiazole and triazole is reported. Taking advantage of the Fiesselmann reaction, reactive bithiophene synthons having alkyl or alkoxy substituents at designated positions are prepared. Following a synthetic strategy, featuring the bottom-up approach, se...

Hydrocarbon exploration has been underway in the north of West Siberia for several decades. Giant gas fields on the Yamal Peninsula are expected to begin feeding the Nord Stream pipeline to Western Europe in late 2012. Employing a variety of highto very high-resolution satellite-based sensors, we have followed the establishment and spread of Bovanenkovo, the biggest and first field to be develo...

In the late 1970s/early 1980s, Baddeley and colleagues conducted a series of experiments investigating the role of eye movements in visual working memory. Although only described briefly in a book, these studies have influenced a remarkable number of empirical and theoretical developments in fields ranging from experimental psychology to human neuropsychology to nonhuman primate electrophysiolo...

Red upconversion luminescence (UCL) is selectively enhanced by about 7 times via Fe(3+) codoping into a NaYF4:Yb,Er nanocrystalline lattice. The maximum red-to-green ratio (R/G) as well as the overall integrated UCL intensity features at an Fe(3+) content of 20 mol%. The size and phase of nanocrystals are simultaneously manipulated via Fe(3+) doping with various concentrations by a facile hydro...

If the thoracoabdominal partitioning of volumes in the mechanical respiratory apparatus was constant, one transducer of indirect spirometry should be sufficient to measure volume variations. To verify this hypothesis we used respiratory inductive plethysmography (RIP) in 16 paralysed patients, of whom eight had normal lungs and 8 had not, to measure: 1) the thoracoabdominal partitioning of volu...

The comparison of fractions is a difficult task that can often be facilitated by separately comparing components (numerators and denominators) of the fractions--that is, by applying so-called component-based strategies. The usefulness of such strategies depends on the type of fraction pair to be compared. We investigated the temporal organization and the flexibility of strategy deployment in fr...

Respiratory volume monitoring (RVM) has been developed to noninvasively measure minute ventilation (V̇E), tidal volume, and breathing frequency and to display real-time respiratory curves in nonintubated patients. Although RVM was originally developed for post-anesthesia and monitored anesthesia care, we describe 3 applications for this monitor in an otherwise austere setting at a missionary hos...

We report herein a simple and convenient luminescent assay for detection of base excision repair enzyme activity using an Ir(III) complex as a G-quadruplex selective probe. Using uracil-DNA glycosylase (UDG) as a model enzyme, the assay achieved high sensitivity and selectivity for UDG over other tested enzymes. The utility of the assay for screening potential UDG inhibitors was also demonstrated.

A set of simplified boundary conditions for a flexible beam connected to a rigid body at one end and free at the other end is presented and applied to the case of a fluidconveying, fluid-immersed pipe. These boundary conditions represent an analytically tractable approximation to those of a submersible which uses a combination of jet action and flutter instability induced tail motion to produce...

This paper presents a novel application of multiparameter spectral theory to the study of structural stability, with particular emphasis on aeroelastic flutter. Methods of multiparameter analysis allow the development of new solution algorithms for aeroelastic flutter problems; most significantly, a direct solver for polynomial problems of arbitrary order and size, something which has not befor...