Chromatographic separations are an emerging technology for the separation of high value products, particularly in the area of pharmaceutics, food, and ne chemicals. The simulated moving bed (SMB) process as a continuous chromatographic separation process is an interesting alternative to conventional batch chromatography, and gained more and more impact recently. The SMB process is realized by c...

Simulated Moving Bed (SMB) chromatography is an important technology for separating chiral compounds, but it can also be used in challenging purifications to remove impurities that are structurally similar to target compounds. Bioxel Pharma, Inc. has developed and implemented a fully automated, high throughput SMB process to remove cephalomannine from paclitaxel, an active pharmaceutical ingred...

1 MAGNETIC RESONANCE IMAGING FOR THE ROTATOR CUFF TEAR Y. Morisawa, T. Sadahiro, Dept, of Orth, Surg, Kochi Prefectural Hata-Kenmin Hospital, Flec Clinic, Kochi, Japan MRI observation of the rotator cuff tear showing the high signal intensity on the supraspinatus muscle belly (SMB) was examined before and after surgery. The subjects were eleven patients with the massive and global rotator cuff ...

Germinal center follicular T helper (GCTfh) cells are essential players in the differentiation of B cells. Circulating follicular T helper (cTfh) cells share phenotypic and functional properties with GCTfh cells. Distinct subpopulations of cTfh with different helper capabilities toward B cells can be identified: cTfh1 (CXCR3+CCR6-), cTfh2 (CXCR3-CCR6-), and cTfh17 (CXCR3-CCR6+). Alterations in ...

Received: 18 April 2008 Revised: 15 August 2008 2nd Revision: 27 January 2009 Accepted: 23 February 2009 Abstract This study presents an empirical investigation of factors affecting smalland medium-sized business (SMB) executives’ decision to adopt anti-malware software for their organizations. A research model was developed by adopting and expanding the protection motivation theory from health...

Plant metabonomic analysis is essential for understanding plant systems responses to osmotic stresses. To understand the comprehensive metabolic responses of Salvia miltiorrhiza Bunge (SMB) to continuous and exhaustive water depletion, we characterized the SMB metabonomic variations induced by three different drying processes using the combined NMR and LC-DAD-MS method. NMR results showed that ...

The present study evaluated the effect of NET-1 siRNA-conjugated sub-micron bubble (SMB) complexes combined with low-frequency ultrasound exposure in gene transfection. The NET-1 gene was highly expressed level in SMMC-7721 human hepatocellular carcinoma cell line. The cells were divided into seven groups and treated with different conditions. The groups with or without low-frequency ultrasound...

This paper aims to explore the optimal marketing channel of e-commerce enterprises with various consumer base size and product added-value in social commerce. By characterizing utility, we construct decision-making models under traditional platform (TECP) two kinds commerce channels involving “e-commerce + social” (ECPS) “social media business’ (SMB). Then, obtain strategy for each by using Kar...

Over recent decades, the South Branch Potomac River, West Virginia, has experienced fish kills and episodes of suppressed health in adult that have spanned small stretches to nearly 120 km contiguous habitat. Although factors such as endocrine disruption, chemical contaminants, infectious agents been detected, no single causal mechanism identified. To gain information about temporal nature abno...

The simulated moving bed (SMB) is a well-established, fully continuous process for chromatographic separation of difficult tasks with overlapping peaks, but it relatively complex. 1-SMB, which uses only one column includes residence time zones to preserve concentration profiles, simpler semi-continuous alternative. This work examines the possible design these zones. Simulation studies were cond...