Chemoprotection refers to the use of specific natural or synthetic chemical agents to suppress or prevent the progression to cancer. The purpose of this study is to assess the protective effect of aspirin, vitamin C or zinc in a dimethyl hydrazine (DMH) colon carcinoma model in rats and to investigate the effect of these supplements on changes associated with colonic zinc status. Rats were rand...

background: in the present study, blood serum level of metals were determined in malarial pa­tients and compared with those in the normal subjects without complication using atomic absorp­tion spectrometer. methods: for the determination of these metals twelve intravenous blood samples each from re­ferred malarial patients and a group of normal subjects were collected and immediately centri­fug...

Background: Chronic hepatitis E virus (HEV) infection may progress to end-stage liver disease in immunosuppressed individuals. Ribavirin therapy is efficient most chronic HEV patients, but 10% remain without a sustained virological response (SVR). Objectives: We aimed study whether zinc supplementation could represent therapeutic approach these patients. Methods: Antiviral properties of salts w...

BACKGROUND Low-birth-weight infants may have impaired zinc status, but little is known about the effect of zinc supplementation. OBJECTIVE The objective was to investigate the effect of daily zinc supplementation on morbidity and anthropometric status in hospital-born, low-birth-weight infants. DESIGN In a double-blind, randomized, placebo-controlled trial, 2052 hospital-born term infants w...

Evidence will be presented that the Alzheimer's disease (AD) epidemic is new, the disease being very rare in the 1900s. The incidence is increasing rapidly, but only in developed countries. We postulate that the new emerging environmental factor partially causal of the AD epidemic is ingestion of inorganic copper from drinking water and taking supplement pills, along with a high fat diet. Inorg...

OBJECTIVE To study the effect of 2 weeks of prophylactic zinc supplementation on incidence and duration of acute respiratory infections. DESIGN Randomized double blind controlled trial. SETTING Community based; urban resettlement area in North-East Delhi, India. PARTICIPANTS 272 children aged 6-11 months with acute respiratory infections. Children receiving zinc supplement within the past...

Given the high prevalence of micronutrient deficiencies and infectious diseases in infants in developing countries, an evaluation of the efficacy of different micronutrient formulations on infant morbidity is a priority. The efficacy of weekly supplementation of four different micronutrient formulations on diarrhea and acute lower respiratory infection (ALRI) morbidity was evaluated in Banglade...

Large-scale use of antibiotics in food animal farms as growth promoters is considered as one of the driving factors behind increasing incidence of microbial resistance. Several alternatives are under investigation to reduce the amount of total antibiotics used in order to avoid any potential transmission of drug resistant microbes to humans through food chain. Copper sulfate and zinc oxide salt...

BACKGROUND Considering the high incidence of low weight and short stature among Iranian children as well as the high prevalence of both mild and moderate types of zinc deficiency, this study was conducted among patients who were referred to the Pediatric Clinic at Massih Daneshvari Hospital during 1997 - 1999. The aim of this study was to determine the effect of zinc supplementation on the chil...