OBJECTIVE The analgesic activity of crude aqueous extract of the root bark of Zanthoxylum xanthozyloides was studied in mice and rats with the view to verifying the claim in folklore medicine that the extract has analgesic activity. METHOD The extract was obtained by Soxhlet extraction and rotatory evaporation, followed by freeze-drying. Groups of rats and mice were, respectively, assigned ra...

Eight lignans (+/-)-syringaresinol, (-)-pinoresinol, (+)-sesamin, (+)-eudesmin, (+)-epieudesmin, (-)-asarinin, (-)-matairesinol, (-)-kobusin, two terpenes lupeol, beta-sitosterol, one aliphatic unsaturated amide, hydroxy-gamma-sanshoöl, and one alkaloid, magnoflorine, were isolated from ZANTHOXYLUM species of Central and South America. Their structures were elucidated mainly by (1)H-, (13)C-NMR...

s The present study is an endeavour to evaluate anti inflammatory and antioxidant activities of ehtanolic extract of steam bark of Zanthoxylum armatum. In vivo anti inflammatory activity was evaluated in wistar species of rats by using carrageenin induced paw edema, where as in vitro antioxidant activity was performed by DPPH free radical method. The plant extract exhibited significant anti-inf...

Objectives: The present study evaluates the antioxidant and cytotoxic activity of different extract (methanol, chloroform, petroleum ether) of Zanthoxylum alatum. Methodology: The antioxidant activities of all the three above mentioned extracts of Zanthoxylum alatum were measured by different in vitro standard methods like 1,1-diphenyl-2-picrylhydrazil radical (DPPH), superoxide anions, nitric ...

Chemical investigation of the EtOAc fraction (EF) obtained from the ethanolic extract of Zanthoxylum naranjillo (Rutaceae) leaves (EE) by preparative HPLC resulted in the isolation of protocatechuic acid (1), gallic acid (2), p-hydroxybenzoic acid (3), and 5-O-caffeoylshikimic acid (4). This is the first time that the presence of compounds 1-4 in Z. naranjillo has been reported. Compounds 1-4, ...

The study evaluated the anthelmintic activity of aqueous extract of Zanthoxylum rhoifolium leaves in two experiments. In vitro test, cultures of goat fecal samples were treated with different concentrations of extract (134.5 to 335.0 mg.mL(-1)). In vivo test was composed of 20 sheep: G1: treated with 0.63 g.kg(-1), during four days; G2: same dose, for eight days; G3: ivermectin (200 microg.kg(-...

In this report, the effects of two oligochitosans, i.e., oligochitosan A (OCHA) and oligochitosan B (OCHB), on control of dry rot of Zanthoxylum bungeanum (Z. bungeanum) caused by Fusarium sambucinum (F. sambucinum) were evaluated. First, both oligochitosans show desirable ability to decrease the infection of F. sambucinum. Second, the oligochitosans strongly inhibit the radial colony and subme...

Natural products have been used for thousands of years for the benefit of mankind, as important sources of food, clothing, cosmetics, building materials, tools, medicines and crop protection agents. They have made enormous contributions to human health through compounds such as quinine, morphine, aspirin (a natural product analog), digitoxin and many others. Researches in this field are becomin...

PREMISE OF THE STUDY Polymorphic microsatellite markers of Zanthoxylum schinifolium (Rutaceae), a promising medicinal plant with effective antibacterial, anticancer, and anti-inflammatory compounds, were developed and evaluated for further genetic studies based on genetic variation among individuals or populations. METHODS AND RESULTS Following the selective hybridization method, microsatelli...