PURPOSE To demonstrate the application of Disability Adjusted Life Year (DALY) as an aid in health outcome measures to evaluate the epilepsy disease burden in rural China and to provide Chinese data to achieve a better understanding of disease burden due to epilepsy. METHODS The DALY is the sum of the number of years of survival with disability (Years Lived with Disability, YLD) and the numbe...

BACKGROUND Viral hepatitis is a major health problem in Brazil and worldwide. The state of Santa Catarina has high endemic areas, and the disease burden is unknown. OBJECTIVES To estimate and analyze the burden of hepatitis B in the state of Santa Catarina, in 2005 - 2010. MATERIALS AND METHODS A time-series analysis was conducted using notification data of incidence and mortality rates fro...

BACKGROUND How to allocate limited vaccine supplies in the event of an influenza pandemic is currently under debate. Conventional vaccination strategies focus on those at highest risk for severe outcomes, including seniors, but do not consider (1) the signature pandemic pattern in which mortality risk is shifted to younger ages, (2) likely reduced vaccine response in seniors, and (3) difference...

INTRODUCTION Health care providers and health policy managers need updated and valid information regarding causes of death (COD) for development the health care facilities, directing primary prevention, assigning funds, and promoting public health. The major causes of death and its burden have not been yet appropriately identified in Iran. Although several studies had been carried out in this a...

BACKGROUND The National Institutes of Health (NIH) is among the world's largest investors in biomedical research, with a mandate to: "…lengthen life, and reduce the burdens of illness and disability." Its funding decisions have been criticized as insufficiently focused on disease burden. We hypothesize that modern portfolio theory can create a closer link between basic research and outcome, and...

Background & Aims: Breast cancer is the second most common cancer in women, with the peak frequency of a decade lower than the global age. The aim of this cross sectional study is to estimate the burden of breast cancer in women in Western Azerbaijan Province in 2013. Materials & Methods:  In this cross-sectional study, the information needed to calculate YLD and YLL creating the total DA...

introduction: disabled-adjusted life year (daly) makes it possible to calculate the time and duration of the disease and its non-fatal consequences along with the time lost due to premature death. this study was aimed to estimate the burden of road traffic accidents (rta) in kermanshah province. methods: to determine the mortality related to road-traffic accidents as well as years of life lost ...

background: cardiovascular diseases are viewed worldwide as one of the main causes of death.this study aims to report the burden of ischemic heart diseases (ihds) in iran by using data of the global burden of disease (gbd) study, 1990-2010. materials and methods: the gbd study 2010 was a systematic eff ort to provide comprehensive data to calculate disability-adjusted life years (dalys) for dis...