Syndecan-1 (CD138), a member of integral membrane heparin sulfate proteoglycans, is an essential matrix receptor for maintaining the normal morphological phenotypes. In this study, we generated a specific mouse anti-human syndecan-1 monoclonal antibody (mAb) 4B3 and identified it by competition assay with the available syndecan-1 mAb (BB4). Stained by 4B3, the expression of syndecan-1 was detec...

Xanthan gum (XG) is a biopolymer obtained in fermentation and used as rheology control agent aqueous systems stabilizing emulsions suspensions. XG, together with other polysaccharides, can form soft, cohesive composite gels. The carbon source the fermentative process responsible for one-third of production costs, search less expensive sustainable alternatives ongoing. use agricultural residues ...

Osteoarthritis (OA) means inflammation of the joints, with the symptoms of joint pain, stiffness, and swelling of the joints. It is a degenerative disease that appears to be caused by both biomechanical and biochemical factors. Intra-articular (IA) injection treatment is one of the main treatment methods for OA because of its positive effect in reducing joint pain and increasing joint mobility....

We report a novel, reproducible methodology which enabled 10 human myeloma cell lines (HMCL) to be obtained from each of 10 tumor samples harvested from 9 patients with extramedullary proliferation. Fresh samples were cultured with interleukin 6 (IL-6) and granulocyte macrophage-colony stimulating factor (GM-CSF) at a high cell density and resulting HMCL growth became progressively dependent on...

K-theoretic Gromov-Witten (GW) invariants of a complex algebraic manifold X are defined as super-dimensions of sheaf cohomology of interesting bundles over moduli spaces of n-pointed holomorphic curves in X. In this paper, we introduce K-theoretic GW-invariants cognizant of the Sn-module structure on the sheaf cohomology, induced by renumbering of the marked points, and compute such invariants ...

Hydrophilic matrices composed of chitosan (CS) and xanthan gum (XG) complexes are of pharmaceutical interest in relation to drug delivery due to their ability to control the release of active ingredients. Molecular dynamics simulations (MDs) have been performed in order to obtain information pertaining to the effect of the state of protonation and degree of N-acetylation (DA) on the molecular c...

An Ontology of Uncertainty, like the one proposed by the W3C’s UR3W-XG incubator group, provides a vocabulary to annotate different sources of information with different types of uncertainty. Here we argue that such annotations should be clearly mapped to corresponding reasoning and representation strategies. This mapping allows the system to analyse the information on the basis of its uncertai...

Francesco Monticone, Constantinos A. Valagiannopoulos, and Andrea Alù Department of Electrical and Computer Engineering, The University of Texas at Austin, Austin, Texas 78712, USA Department of Physics, School of Science and Technology, Nazarbayev University, KZ-010000 Astana, Kazakhstan Center for Nanophotonics, FOM Institute for Atomic and Molecular Physics, Science Park 104, 1098 XG Amsterd...