The effect of cold storage (5 C, 24 h) and heat treatment (60 C, 5 min) of milk on activities of free and membrane-bound xanthine oxidase has been studied. Both treatments enhanced total xanthine oxidase activity in milk. Activity of membrane-bound xanthine oxidase increased and free xanthine oxidase decreased in buttermilk while it increased in skim milk on cold storage. Heat of milk increased...

the major objective of the present study was to characterize the effects of oxidants generated b xanthine (x) plus xanthine oxidase (xo) on isolated rat ileum motility. the effects of three concentrations of x/xo on the basal tone of the rat ileum preparation were studied for 20 minutes. developed tensions were measured in mg/mg tissues and then expressed as percentage of baseline tension. also...

OBJECTIVE Crimean-Congo hemorrhagic fever is an acute viral hemorrhagic fever with a high mortality rate. Despite increasing knowledge about hemorrhagic fever viruses, little is known about the pathogenesis of Crimean-Congo hemorrhagic fever. In this study, we measured serum adenosine deaminase and xanthine oxidase levels in Crimean-Congo hemorrhagic fever patients. METHODS Serum adenosine de...

Levels of reactive oxygen species (ROS) are tightly regulated in mammalian cells. A variety of enzymes produce ROS, including NAD(P)H oxidase, xanthine oxidase, glucose oxidase, myeloperoxidase, the family of nitric oxide synthases, and mitochondrial enzymes.1–4 Low levels of ROS such as superoxide or hydrogen peroxide regulate highly specific targets.5,6 In the cardiovascular system, for examp...

By using a feedback system control scheme, the best combination of formononetin, ononin, calycosin, and calycosin-7-O-β-d-glucoside derived from Astragali Radix was shown to activate a hypoxia response element, a regulator for erythropoietin (EPO) transcription, in kidney fibroblast. In cyclophosphamide-induced anemic rats, the treatment of combined flavonoids, or EPO, improved the levels of re...

Aim: This study was aimed to investigate the levels of antioxidant markers (paraoxonase, superoxide dismutase, glutathione peroxidase, and thiol) oxidative stress (advanced oxidation protein products, xanthin oxidase, nitric oxide, malondialdehyde, 8-hydroxydeoxyguanosine) in pregnant women with chronic hepatitis B C. Material Method: Sixty last trimester, 20 whom had B, another C, remaining we...

Galangin, a non-toxic phytochemical, is known to have variety of therapeutic uses. This study looked into the role inclusion complexes galangin/β-cyclodextrin in increasing antioxidant activity over pure galangin. The this complex comparison In study, hydrogen peroxide assays were used vitro. Galangin demonstrated concentration-dependent scavenging action 2-50 µg mL-1 range, with highest level ...

Punica granatum L. has a long standing culinary and medicinal traditional use in Mauritius. This prompted a comparative study to determine the bioefficacy of the flower, peel, leaf, stem, and seed extracts of the Mauritian P. granatum. The flower and peel extracts resulting from organic solvent extraction exhibited strong antioxidant activities which correlated with the high levels of total phe...

Miracle fruit (Synsepalum dulcificum) belongs to the Sapotaceae family. It can change flavors on taste buds, transforming acidic tastes to sweet. We evaluated various miracle fruit extracts, including water, butanol, ethyl acetate (EA), and hexane fractions, to determine its antioxidant effects. These extracts isolated from miracle fruit exerted potential for reduction of uric acid and inhibite...