............................................................................... . VII Acknowledgement .......................................................................... IX Publications ............................................................................ X List of Figures ........................................................................... XII Chapter 1 Background and Intr...

We examined the acute effect of physical exercise on prefrontal cortex activity in older adults using functional near-infrared spectroscopy (NIRS). Fourteen older adults visited our laboratory twice: once for exercise and once for the control condition. On each visit, subjects performed working memory tasks before and after moderate intensity exercise with a cycling ergo-meter. We measured the ...

The present study examined the hypothesis that working memory deficits contribute to both negative thought disorder and some components of formal thought disorder (discourse coherence and fluency deficits) in individuals with schizophrenia. We examined the language produced by 44 patients with either schizophrenia or schizoaffective disorder during baseline and a dual-task condition designed to...

background: musculoskeletal disorders (msds) are one of the most common causes of occupational injuries that appear mainly in back, neck and upper limb. this study was conducted with the objectives of determination of prevalence rate of msds among workers of a generator manufacturing company and ergonomics assessment of working conditions. methods: in this study, 319 workers randomly selected p...

A total of 72 participants estimated products of complex multiplications of two-digit operands (e.g., 63 x 78), using two strategies that differed in complexity. The simple strategy involved rounding both operands down to the closest decades (e.g., 60 x 70), whereas the complex strategy required rounding both operands up to the closest decades (e.g., 70 x 80). Participants accomplished this est...

Prospective memory is the ability to remember to perform acts in the future. Prospective memory is essential in the aviation domain because it supports a range of tasks including remembering to complete critical radio communications. A wide variety of literature reports that in the laboratory younger adults outperform older adults on many prospective memory tasks. In naturalistic settings howev...

Working memory is mediated by the discharges of neurons in a distributed network of brain areas. It was recently suggested that enhanced rhythmicity in neuronal activity may be critical for sustaining remembered information. To test whether working memory is characterized by unique temporal discharge patterns, we analyzed the autocorrelograms and power spectra of spike trains recorded from the ...

Working memory impairments in schizophrenia have been strongly associated with abnormalities in gamma oscillations within the dorsolateral prefrontal cortex (DLFPC). We recently published the first ever study showing that anodal transcranial Direct Current Stimulation (tDCS) to the left DLPFC was able to significantly improve working memory performance in schizophrenia. In the current paper we ...

Although impairments in working memory (WM) are well documented in schizophrenia, the specific factors that cause these deficits are poorly understood. In this study, we hypothesized that a heightened susceptibility to attentional capture at an early stage of visual processing would result in working memory encoding problems. 30 patients with schizophrenia and 28 demographically matched healthy...