BACKGROUND We evaluated the relationship between thyroid remnant size following thyroidectomy for differentiated thyroid carcinoma and surgical volume and specialisation by assessing pre-ablation radioiodine-131 ((131)I) thyroid bed uptake (TBU) scanning as a surrogate for residual thyroid tissue. METHODS We analysed data of 651 patients in our thyroid cancer database. Patients' data were inc...

Introduction: Differentiated thyroid carcinoma (DTC) follow-up after thyroidectomy and radioiodine-ablation is performed mainly by thyroglobulin (Tg), diagnostic iodine-131 whole body scan (DxWBS) and sonography. Some patients with undetectable Tg have thyroid-bed uptake after ablation in whom decision making regarding the need for retreatment is still controversial. Methods: In this study, we ...

The published studies confirming the safety and efficacy of rhTSH for diagnostic purposes have led to an increased interest in its use for preparation for radioiodine (RI) dose administration in patients with recurrent or persistent differentiated thyroid carcinoma (DTC). In order to establish the efficacy of RI therapy after rhTSH, we have reviewed 39 rhTSH-aided radioiodine treatment in a ser...

Fetuses whose mothers are treated with radioiodine after approximately 10–12 weeks of pregnancy are at high risk of developing iatrogenic hypothyroidism (1). Other than this well-documented occurrence, there is no evidence of harm to others from radiation originating from patients treated with radioiodine. Given that radioiodine is concentrated in breast milk and radioiodine has been documented...

  This report presents a 3.5-year-old boy who was hospitalized for limping. Medical history and physical exams were not suggestive for any definitive diagnosis. Laboratory and radiographic exams did not support any specific diagnosis either. Subsequently bone scan was performed and increased activity in the ankle due to cuboid fracture was incidentally observed.

The presence of distant metastases from differentiated thyroid carcinoma decreases the 10-year survival of patients by 50%. Bone metastases represent a frequent complication especially of follicular thyroid cancer and severely reduce the quality of life causing pain, fractures, and spinal cord compression. Diagnosis is established by correlating clinical suspicion with imaging. Imaging is essen...

Background: Induction of radioadaptive responses in cells pretreated with a low dose radiation before exposure to a high dose is well documented by many investigators. The aim of this study is to determine the frequency of chromosomal aberration in peripheral blood lymphocytes of patients treated by radioiodine (131I) for hyperthyroidism, with or without previous thyroid scan with 99mTc. Materi...

(131)I is an integral component in postsurgical management of well-differentiated thyroid cancer (WDTC), which includes papillary and follicular types. (131)I is used postsurgically to either destroy remaining thyroid tissue (thyroid ablation) or to treat recurrence and metastases (radioiodine therapy). (131)I is no longer a routine diagnostic modality, but it is widely used for remnant ablatio...

a 10-year-old boy was referred to us for evaluation of fuo accompanied with bone pain in both calves. three hours after intravenous injection of 13 mci of 99mtc-mdp, whole body scan in multiple spot views was performed. the scan showed symmetrical areas of diffusely increased tracer uptake in multiple long bones. histopathologic evaluation confirmed osteosclrosis and fibrotic changes without an...

AIM The aim of this study was to compare the efficacy and adverse effects of radioiodine (131I) therapy between two groups of patients with low-risk differentiated thyroid cancer (DTC) who received 30 mCi or 100 mCi radioiodine for ablation of the thyroid remnant after total thyroidectomy. METHODS The study cohort was 173 patients, 85 of whom were given 30 mCi of radioiodine and the others we...