introduction transfusion of red blood cells is a key component in the resuscitation of massively hemorrhaging patients post-injury. little is known about the functional status of patients at discharge or the outcome of patients after discharge from acute hospitalization. we assessed the changes among major trauma patients who had received massive transfusions. materials and methods this article...

A term male infant was noted at birth to have petechiae over the face and trunk and a platelet count of 3 x 10(9) per L. Maternal immune thrombocytopenia (ITP) was suspected from the clinical data and confirmed by the presence of antiplatelet antibody (both in the mother and infant) detected by recently described flow cytometry method. Initial treatment with exchange transfusions, platelet tran...

Polycythemia is defined as a venous hematocrite above 65%. The relationship between viscosity and hematocrite is almost linear till 65% and exponential thereafter. The etiology of polycythemia is related either to intrauterine hypoxia or secondary to fetal transfusion. Most polycythaemic infants are asymptomatic. Increased viscosity of blood may be associated with symptoms of hypoperfusion. Cli...

BACKGROUND Despite limited data, international guidelines recommend the use of intravenous immunoglobulin (IVIg) in neonates with rhesus hemolytic disease. OBJECTIVE We tested whether prophylactic use of IVIg reduces the need for exchange transfusions in neonates with rhesus hemolytic disease. DESIGN AND SETTING We performed a randomized, double-blind, placebo-controlled trial in neonates w...

Transfusion affects the immune response to renal transplantation and may be associated with recurrence of various human neoplasms. Data from patients with colonic, rectal, cervical, and prostate tumours showed an association between transfusion of any amount of whole blood or larger amounts of red blood cells at the time of surgery and later recurrence of cancer. Recipients of one unit of whole...

INTRODUCTION The irradiation of blood components is used to inactivate T-lymphocytes to prevent transfusion-associated graft-versus-host (GVH) disease in susceptible recipients. X-irradiation can be used as an alternative to gamma irradiation and does not involve the use of a radioactive source. This study investigated the effect of X-irradiation on the quality of various red cell concentrates ...

In the Royal Maternity Hospital, Belfast, in common with other centres treating haemolytic disease of the newborn, the number of infants requiring exchange transfusion has been increasing steadily in the past few years. In 1950 there were seven live-born affected infants, of whom five were treated, all successfully, by exchange transfusion, in 1954 there were 42 live-born affected infants of wh...

The importance of warming up the whole blood before transfusion , parti -cularly when large amounts of stored blood is used for patients in shock or under general anesthesia is discussed. Var­ious methods of Warming blood is presn­tcd and the use of high frequency Ele­ctromagnetic field for this purpose and its adv1mtagcs is introduced. 

The first recorded case of recovery from hepatic coma after an exchange blood transfusion was that of Lee and Tink (1958). They gave two exchange transfusions of fresh blood to a boy aged 13 who was deeply jaundiced and comatose. After the first transfusion of 3,260 ml. his condition was unchanged, but when a second exchange of 3,140 ml. was given he improved and recovered completely. Trey et a...