OBJECTIVES: To determine whether oral administration of FA inhibits HNSCC tumor growth in an animal model. STUDY DESIGN: In vivo murine model, two arm controlled study. METHODS: Thirty-eight 5 week old athymic nude mice were randomly assigned to a fusaric acid treatment group (1 mg/mL) (n=19) or a sterile saline group (n=19). A left, lateral flank subcutaneous injection of 2.0x 106 SCC-1 cells ...

The eXtensible Markup Language (XML) is regarded generally as having promise of becoming established as the general purpose framework for enabling transfer of data amongst heterogeneous environments. It is of interest therefore to analyse how suitable it may be once details of applications requirements and constraints are taken into account. One important requirement is for the security of docu...

It is believed in the West that logic began with Aristotle, and that logic is universal. The core of Western thought—including present-day formal mathematics and the philosophy of science—is premised on the belief that logical truths are universal, that they are necessary truths, and that logical deduction is certain and infallible. These beliefs about logic however are untenable, both historic...

A retrospective study was carried out to assess the incidence of cardiomyopathy in western Denmark (Jutland and Funen) (population 2 798 000) during a two year period (1980-81). The WHO/ISCF classification was strictly followed, and rigid criteria for exclusion and inclusion of patients were adopted. Thus cases in which specific heart muscle disorders (myocarditis, alcoholic heart disease, hype...

AN IMPROVED UNDERSTANDING of the terms fertilizer-use efficiency (FUE) and maximum economic yield (MEY) has likely never been as important to western Canadian agronomists and farmers as it is today. The objective of PPI/PPIC and Foundation for Agronomic Research (FAR) sponsored research projects in western Canada is to support a better understanding of the role of phosphorus (P) and potassium (...

Like theology and ethics generally, bioethics has increasingly developed a global consciousness. Controversies over AIDS research and access to affordable AIDS treatment have generated new awareness about the importance of international collaboration as well as the difficulty of achieving moral consensus across economic, political, and cultural divides. Advances in scientific and medical knowle...

Rapid, quantitative Western blotting is a long-sought bioanalytical goal in the life sciences. To this end, we describe a Western blotting assay conducted in a single glass microchannel under purely electronic control. The μWestern blot is comprised of multiple steps: sample enrichment, protein sizing, protein immobilization (blotting), and in situ antibody probing. To validate the microfluidic...

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The aim of this article is to present to the reader a broad view of the work of a general hospital in West Africa in its relation to the health of children. Facts and impressions were accumulated by the author during a year's sojourn in Nigeria, too short a time no doubt for a penetrating survey of local problems, but, possessed of the clinical potential of a flourishing and well-esteemed young...

The media is a powerful presence in people’s lives. Within the field of communication, media is the term used to refer to the particular medium used to deliver a message to a large, anonymous, diverse audience (Pearce, 2009a). Media studies involve research on media effects, which refer to the influence that the media has on audiences, and media representations, which are portrayals of various ...