l(f)=(-l)“(Pof’“‘)‘“‘+(-l)“-‘(p,f’”-”)’”~”+ ... +p,f=A.rf (0.1) on a finite or infinite interval (a, b) with real, locally summable coefficients l/PO,Pl, ..-3 Pnv r under the assumptions that p0 >O and that the weight function r changes its sign on (a, b). If r is positive, problem (0.1) can be studied in the context of Hermitian and self-adjoint operators in the Hilbert space L*(r) with the in...