Deficits in sleep and circadian organization have been identified as common early features in patients with Huntington’s disease that correlate with symptom severity and may be instrumental in disease progression. Studies in Huntington’s disease gene carriers suggest that alterations in the electroencephalogram may reflect underlying neuronal dysfunction that is present in the premanifest stage...

The electroencephalogram displays various oscillation patterns during wake and sleep states, but their spatiotemporal distribution is not completely known. Local field potentials (LFPs) and multiunits were recorded simultaneously in the cerebral cortex (areas 5-7) of naturally sleeping and awake cats. Slow-wave sleep (SWS) was characterized by oscillations in the slow (<1 Hz) and delta (1-4 Hz)...

emergence of primary signs of muslims uprising in tunisia, egypt, libya, bahrain, yemen, and, in a somehow limited form, in arabia and jordan against local tyranny and foreign colonization, made big powers and western expansionist countries to expropriate public movements to their own benefit and to deviate such movements from their true path. in fact, the matter of process or project nature of...

This research has been carried out to determine the marine propeller hydro-acoustic characteristics by Reynolds-Averaged Navier-Stokes (RANS) solver in both uniform and non-uniform wake flow at different operating conditions Wake flow can cause changes in pressure fluctuation and gas effect on propeller noise spectrum. Noise is generated by the induced trailing vortex wake and induced pressure ...

in this study, changes in speed and turbulence intensity in the wake of a peugeot model and the drag coefficient changes with increases vehicle speed in unsteady flow measured and evaluated. the blow open circuit wind tunnel to simulate fluid flow is used. disturbances and nominal maximum speed of the device, respectively is, 30 m / s and 0.01%. has been continuously increasing speed by an inve...

During the sleep onset period (SOP), there is a state-specific relative advantage of the right hemisphere (RH). This superiority could either be due to the ability of the RH when operating at levels of reduced arousal, as suggested by its superiority in sustaining vigilance, or it could depend on a more pronounced homeostatic deactivation of the left hemisphere (LH). To evaluate whether variati...

State-dependent aspects of consciousness are explored with particular attention to waking and dreaming. First, those phenomenological differences between waking and dreaming that have been established through subjective reports are reviewed. These differences are robustly expressed in most aspects of consciousness including perception, attention, memory, emotion, orientation, and thought. Next,...

In addition to cognitive decline, individuals affected by Alzheimer's disease (AD) can experience important neuropsychiatric symptoms including sleep disturbances. We characterized the sleep-wake cycle in the TgCRND8 mouse model of AD, which overexpresses a mutant human form of amyloid precursor protein resulting in high levels of β-amyloid and plaque formation by 3 months of age. Polysomnograp...

BACKGROUND In sleep efficiency monitoring system, actigraphy is the simplest and most commonly used device. However, low specificity to wakefulness of actigraphy was revealed in previous studies. In this study, we assumed that sleep/wake estimation using actigraphy and electromyography (EMG) signals would show different patterns. Furthermore, each EMG pattern in two states (sleep, wake during s...